This comprehensive and concise presentation of genetic factors in cardiovascular disease and their response to therapy consolidates knowledge of this high-interest and emerging topic. Covering broad areas of contemporary genomic medicine and specific cardiovascular diseases, this book is a must for anyone seeking to better understand this rapidly developing field.
Table of Contents
Provisional list of contents.
Section A: Principles.
1 Principles of genetics and genomics.
2 Candidate gene and genome-wide association approaches.
3 A primer in statistical methods in genetics.
4 Ethical, legal, and social issues.
5 The role of ethnicity in managing cardiovascular patients.
6 Moving to the bedside: When? How?.
Section B: Specific cardiovascular disease.
7 Genomics and Atrial Arrhythmias.
8 Ventricular arrhythmias and sudden death.
9 Hypertrophic Cardiomyopathy and Other Forms of Hypertrophy.
10 Genetics and genomics of dilated cardiomyopathy.
11 Arrhythmogenic Right Ventricular Cardiomyopathy.
12 Genetics of atherosclerosis.
14 Stroke Genomics.
16 Case study: warfarin pharmacogenetics from single to multiple genes.
17 Pharmacogenetics and Pharmacogenomics
Dan M. Roden, M.D., Professor of Medicine and Pharmacology, Director, Oates Institute for Experimental Therapeutics, Assistant Vice-Chancellor for Personalized Medicine, Vanderbilt University School of Medicine.