Monitoring is a major component of management of chronic diseases such as diabetes, cardiovascular disease, arthritis and depression. Yet poor monitoring means healthcare costs are rising.
This book discusses how monitoring principles adopted in other spheres such as clinical pharmacology and evidence-based medicine can be applied to chronic disease in the global setting. With contributions from leading experts in evidence-based medicine, it is a ground-breaking text for all involved in delivery of better and more effective management of chronic illnesses.
Table of Contents
Part 1 The Theory of Monitoring
1 An introduction to monitoring therapeutic interventions in clinical practice
2 A framework for developing and evaluating a monitoring strategy
3 Developing monitoring tools: integrating the pathophysiology of disease and the mechanisms of action of therapeutic interventions
4 Biomarkers and surrogate endpoints in monitoring therapeutic interventions
5 Choosing the best monitoring tests
THE CONTROL PHASES
6 Monitoring the initial response to treatment
7 Control charts and control limits in long-term monitoring
8 Developing a monitoring schedule: frequency of measurement
9 How should we adjust treatment?
THE PSYCHOLOGY OF MONITORING
10 Monitoring as a learning and motivational tool
11 Monitoring from the patient's perspective
THE EVALUATION OF MONITORING TECHNIQUES
12 Evaluating the effectiveness and costs of monitoring
14 Point-of-care testing in monitoring
15 Monitoring for the adverse effects of drugs
Part 2 The Practice of Monitoring
16 Monitoring diabetes mellitus across the lifetime of illness
17 Oral anticoagulation therapy (OAT)
18 Monitoring cholesterol-modifying interventions
19 Monitoring levothyroxine replacement in primary hypothyroidism
20 Monitoring in renal transplantation
21 Monitoring in pre-eclampsia
22 Monitoring in intensive care
23 Monitoring intraocular pressure in glaucoma
24 Monitoring in osteoarthritis
About the Author
Professor Paul Glasziou, University of Oxford, Department of Primary Health Care and Director of the Centre for Evidence-based Medicine, Oxford. Paul is a leading figure in evidence-based medicine. He teaches courses and organises workshops both at the Centre in Oxford and the other centres around the world (eg McMaster, Bond University- Australia).
Les Irwig, Professor in the School of Public Health, University of Sydney He teaches courses on diagnostic test assessment, meta-analysis and guideline development, and advanced epidemiological methods. He is especially interested in the application of epidemiological methods to provide the evidence on which to base public health and clinical decisions.
Dr Jeffery Aronson, Clinical Reader in Pharmacology, University of Oxford, UK.