About this book
- Second edition of successful reference on steroid analysis
- Includes a completely new chapter on pharmaceutical aspects of steroid analysis
- Offers a comprehensive and up-to-date review of steroid analysis written by experts in the field
- Features a strong focus on developments in steroid analysis since 1995
This comprehensive and up-to-date 2nd edition of the Steriod Analysis handbook, written by a team of distinguished experts from around the world concentrates on the analysis of steroids in biological fluids. This edition is based on the same format as the first, primarily dealing with analysis of low levels of steroid analytes in biological fluids, but including an extra chapter on pharmaceutical aspects of steroid analysis. Spectroscopic and other methods, including UV and IR absorption spectroscopy, NMR spectroscopy, mass spectrometry, X-ray diffraction, chromatography and immunoassay of steroids are treated in detail. Extraction, purification and quantitation is followed by analysis of specific steroid groups, such as progestagens, estrogens, corticosteroids and anabolic steroids. The editors have made a conscious decision to leave the first edition to stand on its own with regards to steroid analysis prior to 1995 and authors therefore were asked to review the modern post-1995 steroid scene.
This book should be of interest to analytical chemists, biochemists and chemical pathologists working on medical steroids.
Written for » Research
Keywords » DSI_D018 - Extraction, separation and quanitation - Steroid Analysis - analysis of androgens - analysis of corticosteroids - analysis of estrogens - analysis of progestagens - analysis of vitamin D - analytes in complex matrices - biological fluids - detection of anabolic steroids - doping and detection - immunoassay of steroids - industrial steroid analysis - measurement of steroids - medical steroids - methods of steroid analysis - steroid analysis handbook - steroid hormone assays
Related subjects » Analytical Chemistry - Biochemistry & Biophysics - Chemistry - Pathology
Table of contents
Chapter 1. Structure and Nomenclature of Steroids Chapter 2. Spectroscopic Methods of Steroid Analysis Chapter 3. General Methods for the Extraction, Purification and Measurement of Steroids by Chromatography and Mass Spectrometre Chapter 4. Immunoassay of Steroids Chapter 5. Analysis of Corticosteroids Chapter 6 Analysis of Androgens their Derivatives Chapter 7. Analysis of Progestagens Chapter 8 The Measurement of Estrogens Chapter 9. Anabolic steroids: Metabolism, doping and detection in human and equestrian sports Chapter 10. Analysis of Bile Acids Chapter 11. Analysis of Vitamins D, Structural Analogs and their Metabolites Chapter 12. Industrial and Compendial Steroid Analysis Chapter 13. Quality Management of Steroid Hormone Assays
Authors & Editors
Hugh Makin obtained his PhD at the institute of Child Health, University of London in 1966 and was awarded the degree DSc in 1996 for his research on steroid analysis. He has been successively Lecturer, Senior Lecturer and Professor in the Department of Clinical Biochemistry at St. Bartholomew's & the Royal London School of Medicine & Dentistry since joining the Medical School in 1967. His research interests involve the use of GC-MS for the measurement of vitamin D metabolites and, in collaboration with Glen Jones, the use of mass spectrometry for the identification of calcitriol analogue metabolites both in vivo and in vitro. Hugh was the Programme Adviser to the UK Food Standards Agency Phytoestrogen Research Programme which supported a phytoestrogen quality assurance scheme organised by the Institute of Food Research in Norwich.
D.B. Gower is emeritus professor of steroid biochemistry at the University of London, United Kingdom. He holds a B.S. in chemistry from the University of London, a Ph.D. in biochemistry from the University of London and was awarded a D.Sc. from the University of London for his research into the biochemical mechanisms for the control of steroid hormone formation. Professor Gower is a fellow of the Royal Society of Chemistry, a fellow of the Institute of Biology and a chartered chemist.
`...this is an excellent, comprehensive book and can be highly recommended to those who want an up-to-date reference on steroid analysis.' - Analyst