Approximately ten percent of the world population are affected by kidney diseases, which often can only be diagnosed by renal biopsy. This practical guide offers an algorithmic, deductive approach to the interpretation of this complicated procedure, covering all technical methods used for diagnosis. This new edition includes an authoritative chapter on digital renal pathology, a topic inadequately covered in current literature. All chapters have been extensively revised in light of major advances in the understanding of the pathogenesis and clinicopathological features of renal disease. Written for practising pathologists and nephrologists, this text encompasses the entire spectrum of medical renal diseases in both pediatric and adult populations. Its numerous diagnostic algorithms provide a convenient overview and a helpful guide into the detailed text, directing the reader to major patterns of interest. Including online access to over 1000 photomicrographs and diagrams, this book is also of interest to trainees in nephrology and pathology.
• Situated on the midpoint between encyclopaedic and summary coverage • Includes a 'clinical and pathologic' classification scheme, which does not require prior knowledge of what the diagnosis is to find the relevant entry • Extensively revised to incorporate major advances in the pathogenesis, classification and molecular genetics of renal diseases in both native and transplant kidneys
Foreword; Preface to the first edition; Preface to the second edition; 1. Renal development and anatomy William L. Clapp; 2. Renal biopsy: the nephrologist's viewpoint Samir V. Parikh, Alejandro Diez, Isabelle Ayoub, Anthony Alvarado and Brad H. Rovin; 3. Algorithmic approach to the interpretation of renal biopsy Xin Jin (Joseph) Zhou, Zoltan G. Laszik, Tibor Nadasdy and Vivette D. D'Agati; 4. Glomerular diseases associated with nephrotic syndrome and proteinuria Michael B. Stokes, Glen S. Markowitz and Vivette D. D'Agati; 5. Glomerular diseases associated primarily with asymptomatic or gross hematuria Xin Jin (Joseph) Zhou and Ramesh Saxena; 6. Infection-related glomerulonephritis, membranoproliferative pattern of glomerulonephritis and nephritic syndrome Xin Jin (Joseph) Zhou, Michael Kuperman, Nilum Rajora and Ramesh Saxena; 7. Glomerular diseases associated with crescentic glomerulonephritis (rapidly progressive glomerulonephritis) Anjali A. Satoskar and Tibor Nadasdy; 8. Systemic lupus erythematosus and other autoimmune diseases (mixed connective tissue disease, rheumatoid arthritis, and Sjogren's syndrome) Michael B. Stokes, Samih H. Nasr and Vivette D. D'Agati; 9. Metabolic diseases of the kidney Kuang-Yu Jen and Zoltan G. Laszik; 10. Thrombotic microangiopathies Zoltan G. Laszik; 11. Renal diseases associated with hematopoietic disorders or organized deposits Guillermo A. Herrera; 12. Tubulointerstitial diseases Shane M. Meehan and Tibor Nadasdy; 13. Hypertension and vascular diseases of the kidney Kuang-Yu Jen and Jean L. Olson; 14. Cystic and developmental diseases of the kidney Xin Jin (Joseph) Zhou and Ramesh Saxena; 15. The ageing kidney and end stage renal disease Xin Jin (Joseph) Zhou and Ramesh Saxena; 16. Pathology of renal transplantation Tibor Nadasdy, Anjali Satoskar and Gyongyi Nadasdy; 17. Digital renal pathology Anthony J. Demetris, Andrew Lesniak and Kumiko Isse; Index.
Xin Jin (Joseph) Zhou
Baylor University Medical Center, Dallas
Zoltan G. Laszik
University of California, San Francisco
Ohio State University
Vivette D. D'Agati
Columbia University, New York