Nutraceuticals and Health. Review of Human Evidence

Description

Although health claims for nutraceuticals range from the fantastic to the sublime, most of these claims are based on cell culture studies and have not been validated in humans, making them inadequate for public health recommendations. Focusing on human population-based research (epidemiology studies), Nutraceuticals and Health: Review of Human Evidence explores the role of nutraceuticals in human health, disease prevention, health promotion, and as an adjunct to disease treatment.

The editors and their team of recognized experts deliver a comprehensive scientific review of the latest research. The book opens with a general background of nutraceuticals and human health, then covers health and disease areas such as cancer, lipidermia and cardiovascular disease, metabolic syndrome with obesity, diabetes and hypertension, respiratory health, the gut microbiome, and cognitive decline. It then concludes by addressing the methodological issues that must be addressed in the conduct of epidemiological research on nutraceuticals in health and disease.

Although nutraceuticals hold significant promise in alleviating the suffering from disease, for this potential to be fulfilled, much more research is needed to document safety and disease risks in humans. Addressing important knowledge gaps, the book includes cutting-edge summaries that highlight both the biological and epidemiological findings of relevant studies of nutraceuticals in health and disease. Taking an unusual, yet crucial epidemiological focus, it examines whether, and what kinds of, evidence exist to support a role for nutraceuticals in disease risk, prevention, and treatment.

Contents

Introduction

Background to Nutraceuticals and Human Health

Dipanwita Dutta and Yashwant Pathak

Cancer

Clinical Trials of Dietary Supplements and Cancer

Shanti D. Mahabir, Renjit Thomas, Somdat Mahabir

Curcumin in Human Cancer Prevention and Treatment

Adeeb Shezad and Young Sup Lee

Cancer Prevention Potential of Diet and Dietary Supplements in Epigenome Modulation

Zdenko Herceg

Lipidemia and Cardiovascular Diseases

Role of Dietary Supplements in LDL Cholesterol Lowering

Prabhjot S. Nijjar

Nutraceuticals and Atherosclerosis: Human trials

Lina Badimon, Teresa Padro, Gemma Vilahur

Nutraceuticals in Cardiovascular Disease: Mechanisms and Applications

Srinivas M. Tipparaju, Jared Tur, Siva K. Panguluri

Metabolic Syndrome: Obesity, Diabetes and Hypertension

Potential of Nutraceuticals against Obesity Complications

Kylie Conroy, Isobel Davidson and Mary Warnock

The Role of Nutraceutical Supplements in the Prevention and Treatment of Hypertension

Mark C. Houston

Nutraceuticals in the Treatment of Metabolic Syndrome

Francesco Visioli

Medicinal Herbs and Dietary Supplements in Diabetes Management

Poonam Tripathi and Awanish Kumar Pandey

Respiratory Health

Nutrients for Optimal Lung Function

Susan Ettinger

Gut Microbiome

Nutraceutical-Gut Microbiome Interactions in Human Disease

Mukesh Verma

Metabolic and Potential Health Benefits of Nutraceuticals on Gut Micorbiome

Malay K. Das and Yashwant Pathak

Cognitive decline & Neurodegeneration

Nutraceuticals in the Prevention of Cognitive Decline

Zhenzhen Zhang and Joseph L Su

Nutraceuticals in the Prevention or Treatment of Parkinson's Disease

Elizabeth Mazzio, Fran Close, Karam Soliman

Dietary Supplements and other Alternative Substances for the Treatment of Multiple Sclerosis

Angela Senders, Rebecca Spain and Vijayshree Yadav

Methodological Issues

Methodological Issues Conducting Epidemiological Research on Nutraceuticals

Somdat Mahabir