Xenopus frogs have long been used as model organisms in basic and biomedical research. These frogs have helped unlock basic developmental and cellular processes that have led to scientific breakthroughs and have had practical application in cancer research and regenerative medicine. Xenopus Developmentdiscusses the biology and development of this important genus, and will be a great tool to researchers using these frogs in their research. Divided into four sections, the highlights key Xenopus development from embryo to metamorphosis, and the cellular processes, organogenesis, and biological development.
Table of Contents
Edited by Malgorzata Kloc & Jacek Z. Kubiak
I. Oocyte and early embryo
1. Transcription in the Xenopus oocyte nucleus.
2. RNA Localization during Oogenesis in Xenopus laevis.
3. From Oocyte to fertilizable egg - Regulated mRNA translation and the control of maternal gene expression.
Chad E. Cragle and Angus M. MacNicol
4. Polarity of Xenopus oocytes and early embryos.
5. Germ cell specification in Xenopus.
Mary Lou King
II. Midblastula transition, gastrulation and neurulation
6. The Xenopus embryo as a model system to study asymmetric furrowing in vertebrate
Jacek Z. Kubiak, Isabelle Chartrain and Jean-Pierre Tassan
7. Induction and differentiation of the Xenopus ciliated embryonic epidermis.
Marie Cibois, Pierluigi Scerbo, Virginie Thomé, Andrea Pasini and Laurent Kodjabachian
8. Wnt signaling during early Xenopus development
9. Neural tube closure in Xenopus
Hitoshi Morita, Makoto Suzuki and Naoto Ueno
III. Metamorphosis and organogenesis
10. Primordial germ cell migration.
Aliaksandr Dzementsei and Tomas Pieler
11. Gonad development and sex determination in Xenopus.
Rafal P. Piprek and Jacek Z. Kubiak
12. The Xenopus pronephros: A kidney model making leaps toward understanding tubule development.
Rachel K. Miller, Moonsup Lee and Pierre D. McCrea
13. Development of Neural Tissues in Xenopus laevis.
William A. Muñoz, Amy K. Sater and Pierre D. McCrea
14. The development of the immune system in Xenopus. Louis Du Pasquier Neural Regeneration In Xenopus Tadpoles During Metamorphosis.
Mauricio Moreno, Karina Tapia, Juan Larrain
IV. Novel techniques and approaches (6 chapters)
15. Atomic Force Microscopy Imaging of Xenopus laevis Oocyte Plasma Membrane.
16. Size Scaling of Subcellular Organelles and Structures in X. laevis and X. tropicalis.
Lisa J. Edens and Daniel L. Levy
17. Transgenic approach to retinal regeneration of Xenopus laevis.
18. The Xenopus Model for Regeneration Research.
Ying Chen and Gufa Lin
19. Genomics and genome engineering in Xenopus.
Léna Vouillot, Aurore Thélie, Thibault Scalvenzi and Nicolas Pollet