This concise and practical atlas is a guide to the often challenging pathological interpretation of needle core biopsies, with a focus on the differential diagnosis of benign and malignant conditions in lymph node core biopsies. A wide range of pathological changes is covered, along with diagnostic problems and pitfalls. Conditions include: specific reactive conditions such as Kikuchi lymphadenitis and Castleman disease, non-specific reactive lymphadenopathy, malignant lymphomas commonly encountered in needle core biopsies and non-lymphoid and metastatic disease. Detailed photomicrographs are used to illustrate each condition, covering both histological appearances and immunohistochemical findings. An illustrative case is included in most sections and additional images can be found on the accompanying DVD-ROM. This atlas is an essential reference for consultants and specialist medical trainees in the fields of haematopathology, pathology and haematology.
- All illustrations are obtained from everyday real-life diagnostic practice
- Supplies both morphological and phenotypic information, including tables listing key antibodies required for diagnosis
- Includes illustrative case studies, detailed photomicrographs and diagnostic algorithms
1. Reactive lymph nodes
2. Specific reactive conditions in lymph nodes
3. Classical Hodgkin lymphoma
4. Nodular lymphocyte predominant Hodgkin lymphoma
5. Follicular lymphoma
6. Mantle cell lymphoma
7. Burkitt lymphoma
8. Marginal zone lymphoma and lymphoplasmacytic lymphoma
9. Diffuse large B cell lymphoma
10. Chronic lymphocytic leukaemia/small lymphocytic lymphoma
11. Lymphoblastic leukaemia/lymphoma
12. Nodal mature T cell lymphomas
13. Plasma cell neoplasms
14. Other pathology seen in lymph node needle core biopsies
About the Authors
Alan D. Ramsay, University College London and Royal Free Hospitals, London
Alan D. Ramsay is a Consultant Haematopathologist at University College London Hospitals, London, UK.
Manuel Rodriguez-Justo, University College London and Royal Free Hospitals,
Manuel Rodriguez-Justo is a Consultant Pathologist at University College London Hospitals, London, UK.
Scott J. Rodig, Harvard Medical School
Scott Rodig is an Associate Professor of Pathology at Harvard Medical School and an attending pathologist at Brigham and Women's Hospital, Boston, Massachusetts, USA.