This book presents a structural approach to the evaluation of herbal medicinal products for quality, safety and efficacy. There has been an enormous growth in the market for herbal medicinal products in the last twenty five years. However the rediscovery of natural substances with therapeutic potential has raised questions of quality, safety and efficacy on the part of the consumer and also from health professionals. This book brings together current thinking and practice in these areas highlighting current research. In the light of increasing legislation to enforce better standards for these products and the demand by legislators and the public for assurance of safe and effective use, this book seeks to provide a state-of-the-art review, which informs and guides those who seek to promote their use. This book also gives an overview of the place of ethno pharmacology in the development of herbal medicinal products and discusses good agricultural and collection practices, marker analysis and stability testing which contribute to assessment of good quality of these materials.
Section 1: General Aspects; 1. The Worldwide Phenomenon of Increased Use of Herbal Products - Opportunities and Threats; 2. Approaches to Ensuring and Assessing Activity in Indian Herbal Products; 3. Natural Remedies From the Middle East; 4. Chinese Traditional Medicines-the Challenge of Acceptance By Western Medicine; 5. Chinese Traditional Medicines-Evaluation of Botanical Extracts & Dietary Supplements; Section 2: Pharmacology and Clinical Aspects; 6. Synergy and Polyvalence; 7. From Clinical Evidence to Mechanisms of Action; 8. Herbal Medicines for Functional Gastrointestinal Disorders; 9. Authentication and Quality Assessment of Botanical Products Used in Clinical Research; 10. Therapy for Hepatic Carcinoma Using Herbal Drugs; 11. Relevant Testing of Herbal Products Used to Treat Infections; 12. Natural Products Research in Helicobacter Pylori Infections; 13. Evaluation of the Efficacy of Medicinal Herbal Products Used to Treat Cardiovascular Diseases; 14. Herbal Medicinal Products As Anti-angiogenic Agents-Perspectives and Evaluations; 15. Herbs Affecting the Central Nervous System; 16. Herbs Used to Treat Respiratory Conditions Other Than Infections; 17. Essential Oils in the Treatment of Skin Diseases; 18. Immunomodulatory Ayurvedic Herbal Medicinal Products; 19. Tests on Indian and Peruvian Medicinal Plants Used for Wound Healing; 20. Evidence for Efficacy for Herbal Medicinal Products Used for Conditions Associated with Inflammation; 21. Tests for Antioxidant Activity; 22. Safety and Efficacy of Hachimi-jio-gan - a Chinese Preparation to Counteract Oxidative Damage; 23. Traditional Herbs for Healthcare a Case History with Turmeric; 24. Herbal Medicinal Products Affecting Neurotransmission; 25. Herbal Medicinal Products for Tinnitus; 26. Evaluation of Herbal Medicinal Products Against Herpes Virus Diseases; Section 3: Quality and Safety Aspects; 27. Developing Herbal Medicinal Products with Quality, Safety and Efficacy; 28. Quality Control of Chinese Herbal Drugs; 29. Shelf Life of Herbal Remedies; 30. Clinical Trials As Signposts to Efficacy; 31. Toxicological Evaluation; 32. Health Risks Related to HMPS.