Principles of Biochemical Toxicology

This textbook examines mechanisms underlying toxicity, particularly at the molecular level, and factors determing and affecting toxicity. It reflects recent research in the biochemical basis of toxicology and growing concerns over adverse effects of drugs, environmental pollution, and occupational hazards.

The Fourth Edition explains dose response relationships, disposition and metabolism, and toxic responses to foreign compounds. It also includes summary sections, questions and answers, and artwork useful as learning and teaching aids.

New features:

• reorganized sections on basic principles and different types of toxicity
• examples and explanatory diagrams
• risk assessment, export systems, oxidative stress, Thalidomide, Tamoxifen, peroxisome proliferators, domoic acid, benzene, adriamycin, primaquine, biomarkers, cytochrome P450 and other enzymes, receptor mediated effects, endocrine disruption, botox, etc.
• expanded chapter bibliographies