Robert A. Berne, MD, Chairman and Alumni Professor, Department of Physiology, University of Virginia School of Medicine, Charlottesville, Virginia, Bruce M. Koeppen, MD, PhD, Dean, Academic Affairs and Education, University of Connecticut Health Center, Farmington, Connecticut, Matthew N. Levy, MD, Chief, Investigative Medicine, Mount Sinai Hospital, Cleveland, Ohio & Bruce A. Stanton, PhD, Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire.
Physiology is a comprehensive, accurate, up-to-date, and authoritative textbook of human physiology. An emphasis is placed on fundamental mechanisms and concepts and individual concepts are presented via an organ systems approach, clearly describing all mechanisms that control and regulate function. Key experimental observations and examples are included for students who want a better understanding of the body's dynamic process. Clinical relevancy has been enhanced with the addition of shaded boxes highlighting clinical correlations. New pedagogical features include essay questions and a 250-item multiple choice USMLE-type exam.
* Emphasizes fundamental mechanisms and concepts rather than isolated facts--the "bottom line" information. * Key experimental observations and examples are included, for the student who wants a better understanding of the body's dynamic processes. * Presents individual concepts via an organ systems approach, clearly describing all mechanisms that control and regulate functions. * Covers all the hot topics in physiology, such as membrane transport, neurotransmitters, cell and molecular biology, and more.
Cellular Physiology. Cellular Membranes and Transmembrane Transport of Solutes and Water. Ionic Equilibria and Resting Membrane Potentials. Generation and Conduction of Action Potentials. Synaptic Transmission. Membrane Receptors, Second Messengers, and Signal Transduction Pathways. The Nervous System. The Nervous System and Its Components. The Peripheral Nervous System. The Somatosensory System. The Visual System. The Auditory and Vestibular Systems. The Chemical Senses. Spinal Organization of Motor Function. Descending Pathways Involved in Motor Control. Motor Control by the Cerebral Cortex, Cerebellum, and Basal Ganglia. The Autonomic Nervous System and its Central Control. The Cerebral Cortex and Higher Functions of the Nervous System. Muscle. Contractile Mechanism of Muscle Cells. Skeletal Muscle Physiology. Smooth Muscle. The Cardiovascular System. Blood and Hemostasis. The Circuitry. Electrical Activity of the Heart. The Cardiac Pump. Regulation of the Heartbeat. Hemodynamics. The Arterial System. The Microcirculation and Lymphatics. The Peripheral Circulation and Its Control. Control of Cardiac Output: Coupling of Heart and Blood Vessels. Special Circulations. Interplay of Central and Peripheral Factors in the Control of the Circulation. The Respiratory System. Structure and Function of the Respiratory System. Mechanical Properties in Breathing. Pulmonary and Bronchial Circulations: Ventilation/Perfusion Ratios. Transport of Oxygen and Carbon Dioxide: Tissue Oxygenation. Control of Breathing. The Gastrointestinal System. Gastrointestinal Motility. Gastrointestinal Secretions. Digestion and Absorption. The Kidney. Elements of Renal Function. Solute and Water Transport Along the Nephron: Tubular Function. Control of Body Fluid Osmolality and Volume. Potassium, Calcium, and Phosphate Homeostasis. Role of the Kidneys in the Regulation of Acid-Base Balance. The Endocrine System. General Principles of Endocrine Physiology. Whole Body Metabolism. Hormones of the Pancreatic Islets. Endocrine Regulation of Calcium and Phosphate Metabolism. The Hypothalamus and Pituitary Gland. The Thyroid Gland. The Adrenal Glands. The Reproductive Glands.