Hematology and Oncology Subspecialty Consult

Prepared by residents and fellows and reviewed by clinical faculty at the Washington University School of Medicine, this handbook is a practical quick-reference guide to the diagnosis and treatment of hematologic disorders and adult malignancies. It covers both inpatient and outpatient management approaches with the same front-lines practicality as the world-famous Washington Manual® of Medical Therapeutics.

This thoroughly updated Second Edition includes new standards in the treatment of malignancies, mechanisms of action of new therapeutic agents, and the current use of molecular prognostic factors. Key points about diagnosis and management of disorders are bulleted for easy reference. This edition also includes illustrations.

The Washington Manual® is a registered mark belonging to Washington University in St. Louis to which international legal protection applies. The mark is used in this publication by LWW under license from Washington University.

Table Of Contents

HEMATOLOGY

Introduction and Approach to Hematology- Pablo Ramirez
WBC Disorders: Leukopenia and Leukocytosis- Mark A. Schroeder
Red Blood Cell Disorders- Walter W. Chan and Jinny E. Chang
Platelets: Thrombocytopenia and Thrombocytosis- Sakib K. Khalid and Chanda Ho
Introduction to Coagulation and Laboratory Evaluation of Coagulation- Anna Margrét Halldórsdóttir
Thrombotic Disease- Meagan Jacoby and Nathan Marti
Coagulopathy- Lee Demertzis
Myelodysplasia, Bone Marrow Failure Syndromes, and Other Causes of Pancytopenia- Giridharan Ramsingh and Robert Schwartz
Myeloproliferative Disorders- Michael Martin and John Welch
Transfusion Medicine- James C. Mosley, III
Sickle Cell Disease- Meagan A. Jacoby
Drugs That Affect Hemostasis: Anticoagulants, Thrombolytics and Antifibrinolytics- Nasreen Ilias and Mohsen Nasir
Plasma Cell Disorders- Philip E. Lammers and Tanya Wildes

ONCOLOGY

Introduction and Approach to Oncology- Prapti Patel and Tanya Wildes
Cancer Biology- Priya K. Gopalan
Chemotherapy- Kristan M. Augustin and Lindsay M. Hladnik
Introduction to Radiation Oncology- Parag J. Parikh and Imran Zoberi
Breast Cancer- Caron Rigdon and Mariana Chavez-MacGregor
Lung Cancer- Janakiraman Subramanian and Vamsidhar Velcheti
Colorectal Cancer- Coy Heldermon
Other Gastrointestinal Malignancies- David Kuperman
Malignant Melanoma- Mike G. Martin
Head and Neck Cancer- Yee Hong Chia and David Kuperman
Sarcoma- Saiama Waqar and David Kuperman
Endocrine Malignancies- Mark A. Schroeder
Urological Malignancies- Bryan A. Faller and James C. Mosley, III
Gynecologic Oncology- Andrea R. Hagemann and Israel Zighelboim
Intracranial Tumors- Coy Heldermon
The Leukemias- Michael Martin and John Welch
Lymphoma- Todd A. Fehniger
Introduction to Hematopoietic Stem Cell Transplantation- Pablo Ramirez
HIV-Related Malignancies- Giridharan Ramsingh and Nina Asrani
Cancer of Unknown Primary Site- Lukas D. Wartman
Supportive Care in Oncology- Brian A. Van Tine
Oncologic Emergencies- Lukas D. Wartman