• Covers all aspects of the involvement of platelets in disease, split
into four main sections; platelet physiology, bleeding disorders, thrombotic
disorders and antithrombotic therapy
• Key information is summarized at the end of each chapter for quick reference
• Illustrated with simple diagrams of key concepts, in colour throughout
Preface; 1. The structure and production of blood platelets Joseph E. Italiano, Jr; 2. Platelet immunology: structure, functions and polymorphisms of membrane glycoproteins Yasuo Ikeda, Yumiko Matsubara and Tetsuji Kamata; 3. Mechanisms of platelet activation Lawrence Brass and Timothy J. Stalker; 4. Platelet priming Paolo Gresele, Emanuela Dalcinelli and Stafania Momi; 5. Platelets and coagulation José A. López and Ian del Conde; 6. Vessel-wall-derived substances affecting platelets Azad Raiesdana and Joseph Loscalzo; 7. Platelet-Leukocyte-Endothelial cross talk Kevin J. Croce, Masashi Sakuma and Daniel I. Simon; 8. Laboratory investigation of platelets Eduard Shantsila, Timothy Watson and Gregory Y. H. Lip; 9. Clinical approach to the bleeding patient Jos Vermylen and Kathelijne Peerlinck; 10. Thrombocytopenia James Bussel and Andrea Primiani; 11. Reactive and clonal thrombocytosis Ayalew Tefferi; 12. Congenital disorders of platelet function Marco Cattaneo; 13. Acquired disorders of platelet function Michael H. Kroll and Amy A. Hassan; 14. Platelet transfusion therapy Sherrill J. Slichter and Ronald G. Strauss; 15. Clinical approach to the patient with thrombosis Brian G. Choi and Valentin Fuster; 16. Pathophysiology of arterial thrombosis Juan José Badimon, Borja Ibanez and Gemma Vilahur; 17. Platelets and atherosclerosis Stephan Lindemann and Meinrad Gawaz; 18. Platelets in other thrombotic conditions David L. Green, Peter W. Marks and Simon Karpatkin; 19. Platelets in respiratory disorders and inflammatory conditions Paolo Gresele, Stefania Momi, Simon C. Pitchford and Clive P. Page; 20. Platelet pharmacology Dermot Cox; 21. Antiplatelet therapy versus other antithrombotic strategies Nicolai Mejevoi, Catalin Boiangiu and Marc Cohen; 22. Laboratory monitoring of antiplatelet therapy Paul Harrison and David Keeling; 23. Antiplatelet therapy in cardiology Pierluigi Tricoc and Robert A. Harrington; 24. Antiplatelet therapy in cerebrovascular disease James Castle and Gregory W. Albers; 25. Antiplatelet treatment in peripheral arterial disease Raymond Verhaeghe and Peter Verhamme; 26. Antiplatelet treatment of venous thromboembolism Menno V. Huisman, Jaapjan D. Snoep, Jouke T. Tamsma and Marcel M. C. Hovens; Index.