Cerebellar Disorders. A Practical Approach to Diagnosis and Management

Description

During the last three decades, many laboratories worldwide have dedicated their research activities to understanding the roles of the cerebellum in motor control, cognitive processes and the biology of mental processes, behavioral symptoms and emotion. These advances have been associated with discoveries of new clinical disorders, in particular in the field of genetic ataxias, and the growing number of diseases presents a source of difficulty for clinicians during daily practice. This practical guide summarizes and evaluates current knowledge in the field of cerebellar disorders. Encompassing details of both common and uncommon cerebellar ataxias, including vascular, immune, neoplastic, infectious, traumatic, toxic and inherited disorders, this book will assist clinicians in the diagnosis and management of the full spectrum of cerebellar ataxias encountered in daily practice. Essential reading for clinicians, including general practitioners, neurologists, pediatricians, radiologists, psychiatrists and neuropsychologists, this will also prove a valuable tool for students, trainees and researchers.

• Includes the full spectrum of cerebellar disorders encountered in daily practice, emphasizing differential diagnosis
• Includes a classification of cerebellar disorders, detailing common and uncommon cerebellar ataxias, and includes the most recent discoveries in inherited ataxias
• Reviews the basic science behind cerebellar disorders, combining fundamental and clinical aspects

Contents

Preface
Foreword
Introduction
1. Embryology and anatomy
2. Physiology of the cerebellum
3. Symptoms of cerebellar disorders
4. Clinical scales
5. Diagnosis of cerebellar disorders as a function of age
6. Overview of the general management of cerebellar disorders
7. Malformations
8. Cerebellar stroke
9. Immune diseases
10. Endocrine disorders
11. Infectious diseases
12. Corticobasal degeneration
13. Tumors and paraneoplastic disorders
14. Trauma of the posterior fossa
15. Toxic agents
16. Autism spectrum disorders and ataxia
17. Progressive myoclonic epilepsies
18. Multiple system atrophy (MSA)
19. Essential tremor
20. Autosomal Recessive Cerebellar Ataxias (ARCAs)
21. Mitochondrial disorders
22. X-linked ataxias
23. Dominant ataxias
Index.

About the Authors

Mario Ubaldo Manto, University of Brussels
Mario Ubaldo Manto is the Founding Editor of the journal The Cerebellum and the founder of the Society for Research on the Cerebellum (SRC).