Edited by Hiroyuki Ohshima, Tokyo University of Science Faculty of Pharmaceutical Sciences Noda, Chiba, Japan and Kimiko Makino, Professor, Faculty of Pharmaceutical Sciences, Tokyo University of Sciences, Noda, Chiba, Japan
This book provides the reader with information on how colloid and interfaces science forms a basis of pharmaceutical science. Since pharmaceutical science covers a very wide range of life science, in order for pharmaceutical science to develop further, a physicochemical, i.e., colloid and interfacial basis is needed.
Two main problems of colloid and interface science are the interactions of colloidal particles and the response of colloidal particles to external fields. The former is closely related to the stability of drug suspensions and the latter to drug delivery processes, both being the central topics of pharmaceutical science. This clearly illustrates that colloid and interface science is important and necessary to pharmaceutical science.
The readers can obtain knowledge on what colloid and interface science is (Part I) and how it can be applied to pharmaceutical science (Parts II and III). The proposed book is not just a collection of contributions of top scientists in the field but provides systematic description of fundamentals and applications of colloid and interface science in pharmaceutical science.
- Provides a clear description of the fundamentals of colloid and interface science relevant to drug research and development
- Explains the physicochemical/colloidal basis of pharmaceutical science
- Lists modern experimental characterization techniques, provides analytical equations and explanations on analyzing the experimental data
- Describes the most advanced techniques, AFM (Atomic Force Microscopy), SFA (Surface Force Apparatus) in detail
Table Of Contents:
Part I Fundamentals
Interaction between drugs
Response of colloidal drugs to external fields
Aggregation of drugs
Concentrated drug particles
Rheology of colloidal suspensions
Part II Applications of Colloid and Interface Science in Pharmaceutical sciences
Liposomes and micelles
Binding of drugs on liposomes
Drug delivery system
Drug permeation through biological membranes
Part III Measurements
Zeta potential of colloidal drugs
Atomic force microscope
Surface force apparatus