This volume in the Handbook of Clinical Neurology (Series Editors: Michael
J. Aminoff, Department of Neurology, University of California, San Francisco,
USA; François Boller, Bethesda, USA; Dick F. Swaab, Netherlands Institute
for Neuroscience, Amsterdam, the Netherlands) covers the neurological aspects
of HIV/AIDS. The complications of AIDS described include opportunistic infections,
central nervous system tumours, spinal cord disorders, peripheral neuropathies
and progressive encephalopathy. The advances in molecular biology and the advent
of other investigative techniques are described that have transformed the understanding
of the basic mechanisms of the disease and the development of therapeutic strategies.
Despite the much improved prognosis provided by antiretroviral therapy, the
situation is different in the developing world and a chapter highlights the
neurological aspects of HIV/AIDS as found there. This volume gives a comprehensive
account invaluable both to the clinical neurologist and neuroscience researcher.
- A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology.
- International list of contributors including the leading workers in the field.
- Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care.
Table Of Contents:
Introduction to HIV infection and Neuro-AIDS. Neuroepidemiology of HIV/AIDS. HIV neurology in the developing world. The neuropathogenesis of HIV-1 infection. Neurological sequelae of primary HIV infection. AIDS dementia complex. Neurocognitive assessment of eprsons with HIV disease. HIV myelopathy. Peripheral neuropathy of HIV infection. Myopathy in HIV infection. Cerebral toxoplasmosis in AIDS. Cryptococcal infection. Progressive multifocal leukoencephelopathy. Other opportunistic infections of the central nervous system in AIDS. Primary central nervous system lymphoma. Neuroimaging of the HIV/AIDS patient. Cerebrospinal fluid markers in central nervous system HIV infection and AIDS dementia complex. The neuropathology of HIV. Neuropharmavology of HIV/AIDS.
Edited by Peter Portegies, Department of Neurology, OLVG Hospital, Amsterdam, The Netherlands; and Joseph Berger, Department of Neurology, University of Kentucky, Lexington, KY, USA