Perfect for radiation oncology physicians and residents needing a multidisciplinary, treatment-focused resource, this updated edition continues to provide the latest knowledge in this consistently growing field. Not only will you broaden your understanding of the basic biology of disease processes, you'll also access updated treatment algorithms, information on techniques, and state-of-the-art modalities. The consistent and concise format provides just the right amount of information, making Clinical Radiation Oncology a welcome resource for use by the entire radiation oncology team.
New to this Edition
- Two new chapters provide an increased emphasis on stereotactic radiosurgery (SRS) and stereotactic body irradiation (SBRT).
- New Associate Editor, Dr. Andrea Ng, offers her unique perspectives to the Lymphoma and Hematologic Malignancies section.
- Key Points are summarized at the beginning of each disease-site chapter, mirroring the template headings and highlighting essential information and outcomes.
- Treatment algorithms and techniques, together with discussions of controversies and problems, reflect the treatment approaches employed by the authors.
- Disease Site Overviews allow each section editor to give a unique perspective on important issues, while online updates to Disease Site chapters ensure your knowledge is current.
- Disease Site chapters feature updated information on disease management and outcomes.
- Four videos accessible on Expert Consult include Intraoperative Irradiation, Prostate Brachytherapy, Penile Brachytherapy, and Ocular Melanoma.
- Thirty all-new anatomy drawings increase your visual understanding.
- Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
- Content is templated and divided into three sections -- Scientific Foundations of Radiation Oncology, Techniques and Modalities, and Disease Sites - for quick access to information.
- Disease Sites chapters summarize the most important issues on the opening page and include a full-color format, liberal use of tables and figures, a closing section with a discussion of controversies and problems, and a treatment algorithm that reflects the treatment approach of the authors.
- Chapters have been edited for scientific accuracy, organization, format, and adequacy of outcome data (such as disease control, survival, and treatment tolerance).
- Allows you to examine the therapeutic management of specific disease sites based on single-modality and combined-modality approaches.
- Features an emphasis on providing workup and treatment algorithms for each major disease process, as well as the coverage of molecular biology and its relevance to individual diseases.
Table of Contents
SECTION I SCIENTIFIC FOUNDATIONS OF RADIATION ONCOLOGY
Part A. Radiobiology
1. The Biological Basis of Radiation Oncology
2. Molecular and Cellular Biology
3. Dose-Response Modifiers in Radiation Therapy
4. Interaction of Chemotherapy and Radiation
5. Biologics and Their Interactions with Radiation
Part B. Physics
6. Radiation Oncology Physics
7. Radiation Physics - Stereotactic
Part C. Related Cancer Disciplines
8. Surgical Principles
9. Principles of Chemotherapy
10. Imaging in Oncology
11. Nuclear Medicine
12. Health Services Research in Radiation Oncology
13. Statistics and Clinical Trials
14. Late Effects after Radiation
SECTION II TECHNIQUES AND MODALITIES
16. Intensity-Modulated and Image-Guided Radiation Therapy
17. Intraoperative Irradiation
18. Total Body Irradiation
19. Charged Particle Radiotherapy
20. Neutron Radiotherapy
22. Targeted Radionuclide Therapy
23. Stereotactic Irradiation: CNS Tumors
24. Stereotactic Body Irradiation: Extracranial Tumors
25. Metastatic Disease: Bone, Spinal Cord, Brain, Liver, and Lung
SECTION III DISEASE SITES
Part A. Central Nervous System Tumors
26. Low-Grade Gliomas
27. High-Grade Gliomas
28. Benign Brain Tumors: Meningiomas and Vestibular Schwannomas
29. Pituitary Tumors and Craniopharyngiomas
30. Spinal Cord Tumors
31. Orbital, Ocular, and Optic Nerve Tumors
Part B. Head and Neck Tumors
32. Oral Cavity
33. Oropharyngeal Cancer
34. Nasopharyngeal Carcinoma
35. Larynx and Hypopharynx Cancer
36. Sinonasal Cancer
37. Salivary Gland Malignancies
38. Thyroid Cancer
39. Unknown Head and Neck Primary Site
40. Management of the Neck
41. Cutaneous Carcinoma
42. Malignant Melanoma
Part C. Thoracic Neoplasms
43. Small Cell Lung Cancer
44. Non-Small Cell Lung Cancer
45. Cancer of the Esophagus
46. Uncommon Thoracic Tumors
Part D. Gastrointestinal Tumors
47. Gastric/GE Junction Cancer
48. Pancreatic Cancer
49. Hepatobiliary Cancer
50. Colon Cancer
51. Rectal Cancer
52. Anal Carcinoma
Part E. Genitourinary Tumors
53. Prostate Cancer
54. Bladder Cancer
55. Testicular Cancer
56. Kidney and Ureteral Carcinoma
57. Penile Cancer
Part F. Gynecologic Tumors
58. Cervical Cancer
59. Endometrial Cancer
60. Cancers of the Vulva and Vagina
61. Ovarian Cancer
Part G. Breast Cancer
62. Noninvasive Breast Cancer
63. Breast Cancer: Stages I-II
64. Breast Cancer: Postmastectomy Radiation, Locally Advanced Disease, and Inflammatory Breast Cancer
Part H. Sarcoma and Benign Disease
65. Soft Tissue Sarcoma
66. Benign Diseases
Part I. Childhood Cancers
67. Central Nervous System Tumors
68. Pediatric Soft Tissue Sarcomas
69. Pediatric Sarcomas of Bone
70. Wilms? Tumor
73. Pediatric Leukemias and Lymphomas
74. Pediatric Hodgkin's Lymphoma
75. Rare Pediatric Tumors
Part J. Lymphoma and Hematologic Malignancies
76. Hodgkin's Lymphoma
77. Non-Hodgkin's Lymphoma
78. Multiple Myeloma and Other Plasma Cell Neoplasms
79. Mycosis Fungoides
By Leonard L. Gunderson, MD, MS, FASTRO, Emeritus Professor and Consultant, Department of Radiation Oncology, Mayo Clinic College of Medicine and Mayo Clinic, Scottsdale, Arizona and Joel E. Tepper, MD, Hector MacLean Distinguished Professor of Cancer Research, Department of Radiation Oncology, University of North Carolina Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina