From the classroom to the lab, this text provides complete coverage of the latest advances in clinical chemistry. Part one of the text includes content on laboratory techniques and practice, and part two provides detailed descriptions of how specific diseases affect the human body. Plenty of user-friendly features including outlines, key terms, objectives, and internet references make even difficult concepts easy to understand, and the new full-color insert illustrates important concepts in vibrant detail.
•Full coverage of clinical chemistry from experts in the field gives
you a solid foundation for transferring from theory to practice.
•Clear explanations and user-friendly features make this a textbook that you can continue to use as a reference on the job.
•Key terms listed at the beginning of each chapter help you master relevant vocabulary.
•Section objectives highlight the most important content and provide goals for each chapter.
New to this Edition
•New chapters on Laboratory Analysis of Hemoglobin Variants, Laboratory
Approaches to Serology Testing, and Viral Hepatitis: Diagnosis and Monitoring
keep you at the cutting edge of your field.
•Key Concept boxes provide short summaries of key content to help you quickly review information.
Table of Contents
Part I: Laboratory Techniques and Laboratory Management
- 1. Basic Laboratory Principles and Techniques
- 2. Spectral Techniques
- 3. Chromatography and Mass Spectrometry: Theory, Practice, and Instrumentation
- 4. Chromatographic Techniques
- 5. Laboratory Analysis of Hemoglobin Variants NEW!
- 6. Electrophoresis
- 7. Immunological Reactions
- 8. Immunochemical Techniques
- 9. Principles for Competitive-Binding Assays
- 10. Laboratory Approaches to Serology Testing NEW!
- 11. Measurement of Colligative Properties
- 12. Electrochemistry: Principles and Measurement
- 13. Molecular Diagnostics
- 14. Therapeutic Drug Monitoring
- 15. Clinical Enzymology
- 16. Protein Isoforms: Isoenzymes and Isoforms
- 17. Interferences in Chemical Analysis
- 18. Sources and Control of Preanalytical Variation
- 19. Laboratory Management
- 20. Laboratory Automation
- 21. Point-of-Care (Near-Patient) Testing
- 22. Laboratory Information Systems
- 23. Laboratory Statistics
- 24. Reference Intervals and Clinical Decision Limits
- 25. Quality Control in the Clinical Chemistry Laboratory
- 26. Evaluation of Methods
Part II: Physiology and Pathophysiology
- 27. Basic Biochemistry
- 28. Physiology of Body Water and Electrolytes
- 29. Acid-Base Control and Acid-Base Disorders
- 30. Renal Function
- 31. Liver Function
- 32. Viral Hepatitis: Diagnosis and Monitoring NEW!
- 33. Bone Disease
- 34. The Pancreas: Function and Chemical Pathology
- 35. Gastrointestinal Function
- 36. Cardiac and Muscle Disease
- 37. Coronary Artery Disease: Lipid Metabolism
- 38. Diabetes
- 39. Iron, Porphyrin, and Bilirubin Metabolism
- 40. Hemoglobin
- 41. Human Nutrition
- 42. Trace Metals
- 43. Vitamins
- 44. Pregnancy
- 45. The Newborn
- 46. Extravascular Biological Fluids
- 47. Nervous System
- 48. General Endocrinology
- 49. Thyroid
- 50. The Gonads
- 51. Adrenal Hormones and Hypertension
- 52. Diseases of Genetic Origin
- 53. Neoplasia
- 54. Laboratory Evaluation of the Transplant Recipient
- 55. Toxicology
- 56. Addiction and Substance Abuse
By Lawrence A. Kaplan, PhD, DABCC, FACB, Director, Clinical Chemistry, Bellevue Hospital; Clinical Professor, Pathology, New York University, New York, NY and Amadeo J. Pesce, PhD, DABCC, FNACB, Professor, Department of Pathology and Laboratory Medicine, College of Medicine, University of Cincinnati, Cincinnati, OH; Laboratory Director, Adams County Hospital, West Union, OH; Laboratory Director, Drake Center, Cincinnati, OH