- Includes numerous algorithms for managing patients at risk of developing breast cancer and those who already have breast cancer at any stage
- Summarizes results and interprets data from key clinical trials of surgery, radiation therapy, chemotherapy, endocrine therapy
- Extensive discussion on managing advanced or metastatic breast cancer with
emphasis on cutting edge therapies
The single most important fact about breast cancer is the great variation in its natural history and its responsiveness to therapy from one patient to another. The clinician must integrate an assessment of the patient's likely course based on clinical and pathological staging and laboratory studies with objective evidence on the benefits of therapy. The primary aim of this book is to provide the clinician with the tools to do just that. Outcomes of clinical trials and details about commonly used drug regimens, drug dosage, and the expected side effects are summarized in generous tables and figures. Medical terminology has been defined and descriptions of the evolution in our thinking and understanding of the disease are often given to provide perspective in the interpretation of evidence from current studies for busy clinicians and trainees alike.
Readership: oncologists, oncology trainees, radiotherapy and radiology trainees, oncology nurses.
1. Epidemiology and Risk Factors for Breast Cancer
2. Primary and Secondary Prevention of Breast Cancer
3. Premalignant Changes and In Situ Carcinoma
4. Natural History of Invasive Breast Cancer
5. Histology of Breast Cancer
6. Clinical and Pathological Staging
7. Molecular Factors as Prognostic/Predictive Tools and Therapeutic Targets
8. Diagnosis, Work-up, and Follow-up of Breast Cancer Patients
9. Treatment of the Breast and Regional Lymph Nodes Surgery and Radiation Therapy
10. Adjuvant Systemic Therapy
11. Neoadjuvant Therapy and Locally-Advanced or Inflammatory Breast Cancer
12. Management of Metastatic Disease
I. Craig Henderson is a Professor of Medicine at the University of California San Francisico's Helen Diller Family Comprehensive Care Center in San Francisco, California.