About this Book
- Coins the term "molecular psychology" to describe cutting-edge methodology that investigates the nerual bases of behavior.
- Compiles and applies research across clinical neuroscience, genetics, psychology and other fields to study behavior and its neural underpinnings.
- Molecular methods cover candidate genes, genome-wide association studies, copy number variations, gene expression studies, and epigenetics.
- Assembles an interdisciplinary team of leaders and specialists across an array of fields.
Determining the biological bases for behavior, and the extent to which we can observe and explain their neural underpinnings, requires a bold, broadly defined research methodology. The interdisciplinary entries in this handbook are organized around the principle of "molecular psychology," which unites cutting-edge research from such wide-ranging disciplines as clinical neuroscience and genetics, psychology, behavioral neuroscience, and neuroethology.
For the first time in a single volume, leaders in diverse research areas use
molecular approaches to investigate social behavior, psychopathology, emotion,
cognition and stress in healthy volunteers, patient populations, and an array
of non-human species including rodents, insects, fish, and non-human primates.
Chapters draw on molecular methods covering candidate genes, genome-wide association
studies, copy number variations, gene expression studies, and epigenetics while
addressing the ethical, legal, and social issues to emerge from this new and
exciting research approach.
Readership: Psychologists with a biological orientation and neuroscientists with an interest in behavior (using both animal models and humans); clinicians in mental health (clinical psychologists and psychiatrists); researchers in cognitive, behavioral, social, and clinical neuroscience; graduate students in neuroscience and psychology.
Table of Contents
Part I: Introduction and Fundamentals
1. Molecular Psychology: A Brief History and Introduction
2. Complex Trait Genetics and Population Genetics in Psychiatry: A Review of the Methods
Part II: Applications
3. Neuromodulation of Social Behavior in Insects
Stephen J. Simpson and Paul A. Stevenson
4. Social Regulation of Gene Expression in the African Cichlid Fish Astatotilapia burtoni
Karen P. Maruska and Russell D. Fernald
5. Molecular Neurobiology of Social Bonding
Catherine E. Barrett and Larry J. Young
6. Gene-by-Environment Interactions in Primates
Christina S. Barr
7. Genetic Perspectives on the Neurochemistry of Human Aggression and Violence
Joshua W. Buckholtz and Andreas Meyer-Lindenberg
8. Oxytocin and Vasopressin Gene Variation and the Neural Basis of Social Behaviors
Lars Westberg and Hasse Walum
9. Modeling the Genetics of Social Cognition in the Laboratory
10. Gene-by-Environment Mouse Models for Mood Disorders
Maria Razzoli, Alessandro Bartolomucci, and Valeria Carola
11. Neurogenetics of Individual Differences in Brain, Behavior, and Risk for Psychopathology
Luke W. Hyde, Ryan Bogdan, and Ahmad Hariri
12. Copy Number Variation in Neuropsychiatric Disorders
James J. H. Rucker and Peter McGuffin
13. Molecular Foundations of the Symptoms of Major Depressive Disorder
Michael C. Chen and Ian H. Gotlib
14. Is Depression an Infectious Disease?
Emotion, Cognition, and Stress
15. Consequences of Early-Life Experiences on Cognition and Emotion: A Role for Nutrition and Epigenetic Mechanisms
E. F. G. Naninck, P. J. Lucassen, and Aniko Korosi
16. Genetic Tools in the Erasure of Emotional Memory
Derya Sargin, Chen Yan, and Sheena Josselyn
17. Genetics of Autonomic Nervous System Activity
Eco de Geus, Rene van Lien, Melanie Neijts, and Gonneke Willemsen
18. The Genetic Basis of Positive Emotionality
Martin Reuter and Christian Montag
Part III: Science and Society
19. Genetics and Criminal Justice
Stephen J. Morse
Turhan Canli, Associate Professor of Psychology and Radiology, Stony Brook University
Turhan Canli is an Associate Professor of Psychology and Radiology at Stony Brook University, where he is the founder and director of the SCAN (Social, Cognitive, and Affective Neuroscience) Center. He is a past director of the Graduate Program in Genetics. Dr. Canli's research focuses on individual differences in emotion, personality, and social behavior, and integrates tools from psychology, neuroscience, and molecular biology.