Autonomic surgery is an important and expanding field within contemporary clinical practice. Surgical therapies influencing the autonomic nervous system have historically entailed disabling various components of its network by injurious methods. More sophisticated techniques have now emerged to allow modulation of neural function by electrical implants or by preservative surgery. This has fuelled the expansion in this field as safer therapies with greater scope for patient benefit have become available. As the potential for precise neural manipulation has advanced, so has the number and diversity of diseases which have become amenable to such therapies.
This book reviews the basic science underpinning the autonomic control of various body systems and the state-of-the-art clinical applications by which these systems are surgically modulated in patients today. Clinical chapters include details of the procedure, operative considerations, outcomes, adverse effect profile, post-operative management of such patients and reflections on personal experience. Autonomic surgery can be applied to a wide variety of diseases affecting large numbers of the population such as angina pectoris, hypertension, orthostatic hypotension, sexual dysfunction, regional pain syndromes, headache and epilepsy.
- Key clinicians performing these surgeries worldwide have contributed chapters relevant to their practice
- Provides a comprehensive review of the basic science and diverse clinical applications in autonomic surgery
- For the first time all of the current autonomic surgeries are compiled into one authoritative, comprehensive, multidisciplinary publication
- Neural Control of the Heart and Cardiovascular System, Jonathan A. Hyam and Alexander L. Green
- Baroreceptor Activation Therapy: A Surgical Approach to the Treatment of Hypertension, Peter W. de Leeuw and Abraham A. Kroon
- Deep Brain Stimulation and Blood Pressure Disorders, Alexander L. Green, Erlick A. C. Pereira, and Jonathan A. Hyam
- Lateral Medullary Decompression for Essential Hypertension, Peter J. Jannetta and Kenneth F. Casey
- Device-based Approaches to Target Renal Sympathetic Nerves for Hypertension, Markus Schlaich and Murray Esler
- Evolution and Developments in Autonomic Control of the Heart. I: the Neurocardiac Axis, Mike J. L. DeJongste, Gerbrand J. Groen, and Robert D. Foreman
- Evolution and Developments in Autonomic Control of the Heart. II: Therapeutical Interventions, Mike J. L. DeJongste, Michiel Kuijpers, Gerbrand J. Groen, and Robert D. Foreman
- Periarterial Sympathectomy in the Treatment of Upper Extremity Peripheral Vascular Disease, Christian E. Sampson
- Spinal Cord Stimulation for Complex Regional Pain Syndrome. I: Mechanisms, Tim McCormack and Stana Bojanic
- Spinal Cord Stimulation for Complex Regional Pain Syndrome. II: Clinical Applications, Stana Bojanic and Tim McCormack
- Trigeminal Autonomic Cephalalgias. I: Peripheral Neuromodulation (Occipital Nerve and Sphenopalatine Ganglion Stimulation), Sarah Miller, Laurence Watkins, and Manjit S. Matharu
- Trigeminal Autonomic Cephalalgias. II: Deep Brain Stimulation of the Posterior Hypothalamus for Chronic Cluster Headache, Giuseppe Messina, Roberto Cordella, Michele Rizzi, Massimo Leone, and Angelo Franzini
- The Central Nervous System in Control of Continence and Sexual Functions, Thelma Lovick and Gert Holstege
- Pudendal Nerve Stimulation, Philip E. V. van Kerrebroeck and Martijn A. C. Smits
- Sacral Nerve Stimulation for Lower Urinary Tract Dysfunction, Philip E. V. Van Kerrebroeck and Tom A. T. Marcelissen
- Neuromodulation for Faecal Incontinence and Constipation, Emma V. Carrington, Emma H. Horrocks, Charles Knowles, and Noel N. Thin
- Gastric Stimulation for Obesity and Gastroparesis, Edy E. Soffer
- Hyperhidrosis: Pathophysiology and Available Therapies, Brian Perri, Shoshanna Vaynman, Samer Ghostine, Srinath Samudrala, J. Patrick Johnson, and Khawar Siddique
- Vagus Nerve Stimulation in the Treatment of Epilepsy. I: History, Vagus Nerve Physiology, and Putative Mechanisms, Benjamin I. Rapoport and Joseph R. Madsen
- Vagus Nerve Stimulation in the Treatment of Epilepsy. II: Procedure, Evidence, and Adverse Events, Benjamin I. Rapoport and Joseph R. Madsen
Jonathan A. Hyam, Neurosurgical Registrar, Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, University College London, UK,Erlick A. C. Pereira, Senior Neurosurgical Registrar, Department of Neurosurgery, Oxford University Hospitals NHS Trust, UK,Alexander L. Green, Consultant Neurosurgeon, Nuffield Department of Surgical Sciences, University of Oxford, UK
Mr Jonathan A. Hyam is a Neurosurgical Registrar at the National Hospital for Neurology and Neurosurgery, Queen Square, London, and a Visiting Academic at Oxford Functional Neurosurgery and the Nuffield Department of Surgical Sciences, University of Oxford. He was awarded his DPhil in 2012 from the Department of Physiology, Anatomy and Genetics.
Mr Erlick A. C. Pereira is a Senior Neurosurgical Registrar at the Department of Neurosurgery, Oxford University Hospitals NHS Trust, UK. He has published around 90 papers in other areas of surgery and neuroscience. Last year, he gained both his FRCS (Neuro.Surg) and was awarded a DM for research into deep brain surgery for pain.
Mr Alexander L. Green is a Consultant Neurosurgeon at the Nuffield Department of Surgical Sciences, University of Oxford, UK. He is currently president of the British Society for Stereotactic and Functional Neurosurgery (BSSFN).