Imaging in Neurodegenerative Disorders

Description

• Covers state of the art and evolving imaging modalities and research, making this a key resource for all modern techniques
• Chapters are written by world leaders in the field, ensuring clarity and precision throughout the book
• This book offers a synergy between the fields of radiology, neurology and neuroradiology, allowing the reader to have a complete vision of the pathology and its diagnosis

Diagnosing neurodegenerative diseases can prove particularly intimidating to clinicians, because many times the diagnosis cannot be critically "confirmed" by a simple test. New imaging modalities have advanced to the point of high resolution, morphological, metabolic and functional analysis. Computed tomography, magnetic resonance, nuclear medicine and molecular imaging have recently emerged as outstanding non-invasive techniques for the study of the neurodegenerative disorders.

Imaging in Neurodegenerative Disorders covers all the imaging techniques and new exciting methods like new tracers, biomarker, metabolomic and gene-array profiling, potential for applying such techniques clinically, and offers present and future applications as applied to the neurodegenerative disorders with the most world renowned scientists in these fields. This book is an invaluable resource for researchers, clinicians, and trainees in neuroscience, neurology, psychiatry, and radiology.

Readership: Researchers, clinicians, and trainees in neurology, neuroscience, psychiatry, and radiology, as well as other healthcare professionals (particularly radiological technicians), and undergraduate students.

Table of Contents

Section 1: Introduction
1: Giancarlo Logroscino and Rosanna Tortelli: Epidemiology of neurodegenerative diseases
2: Luigi Barberini, Luca Saba, Claudia Fattuoni, Matteo Fraschini, and Francesco Marrosu: Metabolomics of neurodegenerative disorders
3: James D Mills and Michael Janitz: Transcriptome profiling in neurodegenerative disorders
4: Thomas Rapp, Pauline Chauvin, Nadège Costa, and Laurent Molinier: Health economic considerations in neurodegenerative disorders
5: Robert Laforce, M. Lehmann, J. Macoir, S. Poulin, M. Roy, J.-P. Soucy, L. Verret, B. L. Miller, and R. W. Bouchard: Symptoms of neurodegenerative diseases
Section 2: Imaging Technique
6: Michele Anzidei: Computed Tomography
7: Aart J. Nederveen, Matthan W.A. Caan, and Marion Smits: General principles of Magnetic Resonance Imaging
8: Juergen Dukart and Bogdan Draganski: Nuclear medicine and radiology
9: Vivekanandan Palaninathan, Sivakumar Balasubramanian, D. Sakthi Kumar: Molecular imaging and neurodegenerative diseases
10: Christopher Kobylecki, Alexander Gerhard, and Karl Herholz: PET imaging in neurodegenerative disorders - evolving techniques and new tracers
11: Shankar Vallabhajosula, Brigitte Vallabhajosula, and Lilja Solnes: Radiopharmaceuticals for molecular imaging of neurodegenerative diseases
Section 3: Neurodegeneration: Cognition
12: Charles D. Smith and Brian T. Gold: Neuroimaging of Alzheimer's disease
13: F. Garaci, N. Toschi, T. Volpi, G. Gareffa, L. Spies, S.Lista, H. Hampel: MRI-based imaging of Alzheimer's disease
14: Jennifer L. Whitwell: Frontotemporal dementia
15: Claire Henchcliffe and Thomas Tropea: Dementia with Lewy Bodies
16: Luke A Massey and Sean O'Sullivan: Corticobasal Syndrome and Corticobasal Degeneration
Section 4: Nueorregeneration: Movement
17: Ana M. Franceschi, Sofia Pina, and Mauricio Castillo: Parkinson's disease: Clinical and Imaging Features
18: Dominic Paviour: Progressive Supranuclear Palsy (PSP)
19: SJA van den Bogaard and RAC Roos: Imaging in Huntington's disease
20: Keita Sakurai: Multiple system atrophy
Section 5: Neurodegeneration: Strength
21: Martin R. Turner: Amyotrophic Lateral Sclerosis
Section 6: Neurodegeneration: Coordination
22: Ana Solodkin, Gulin Oz, and Christopher M Gomez: Spinocerebellar Atrophies
23: Hamed Akhlaghi, Martin B. Delatycki, Nellie Georgiou-Karistianis, and Gary F. Egan: Imaging in Neurodegenerative Disorder- Friedreich Ataxia
24: Damien Galanaud: Neuroimaging in human prion diseases
Section 7: Neurodegeneration: PNS\ANS
25: Erez Nossek & Tali Jonas Kimchi: Amyloidosis
26: Amogh Hedge and CC Tchoyoson Lim: Metabolic and toxin related neurodegeneration
Section 8: Neurodegeneration: Myelin
27: Eytan Raz: Demyelinating diseases
28: José Berciano and Elena Gallardo: Charcot-Marie-Tooth disease
29: Lev Bangiyev, Alexandra Roudenko, Eytan Raz, August Dietrich, Girish M. Fatterpekar: Neurodegenerative Disorders of the Basal Ganglia
Section 9: Neurodegeneration: Trauma
30: Jan Booij, Françoise J Siepel, Tirza C Buter, and Dag Aarsland: Clinical benefit of dopamine transporter imaging in movement disorders and dementia
31: Erin D. Bigler: Neurodegeneration post trauma: Brain
32: J.A. Petersen, Spyros S. Kollias: Neurodegeneration post trauma: spine
33: Duan Xiao-Hui and Jun Shen: Neurodegeneration post trauma: Peripheral nerves
Section 10: Neuroimaging after therapy
34: A.L. Bartels, R. Hilker: Functional imaging of neurosurgery in Parkinson's disease
35: Tsui A, Piccini P: Neuroimaging after Cell-Based Therapy

Author

Edited by Luca Saba, Associate Professor of Radiology, University of Cagliari, Italy

Luca Saba received the MD from the University of Cagliari, Italy in 2002. Today he works in the Azienda Ospedaliero Universitaria of Cagliari. Dr Saba research fields are focused on Multi-Detector-Row Computed Tomography, Magnetic Resonance, Ultrasound, Neuroradiology, and Diagnostic in Vascular Sciences. Dr. Saba has won 15 scientific and extracurricular awards during his career. He has presented more than 450 papers and posters in National and International Congress (RSNA, ESGAR, ECR, ISR, AOCR, AINR, JRS, SIRM, AINR). He wrote 18 book-chapters and he is Editor of 7 books in the field of Computed Tomography, Cardiovascular, Plastic Surgery, Gynecological Imaging and Neurodegenerative imaging. He is member of the Italian Society of Radiology (SIRM), European Society of Radiology (ESR), Radiological Society of North America (RSNA), American Roentgen Ray Society (ARRS) and European Society of Neuroradiology (ESNR) and serves as Reviewer of more than 30 scientific journals.