Cancer in Children. Clinical Management

Description

• An established and highly regarded introduction to paediatric oncology
• Brings together an international group of highly respected editors and contributors
• Provides evidence-based information on how to investigate and treat the common cancers in childhood, with state-of-the-art descriptions of what is basic and essential for management

Cancer in Children is an established and highly regarded introduction to paediatric oncology. In a clear and concise way, it covers the aetiology, symptoms, and treatment of cancer in children, the complications that can arise during treatment, and the various outcomes of the illness.

This new edition brings together an international group of highly respected editors and contributors to provide evidence-based information on how to investigate and treat the common cancers in childhood. State-of-the-art descriptions of what is basic and essential for management is included; there are new chapters on clinical trials, evidence based practice, the treatment of cancer in less well-resourced countries, stem cell and immunotherapy, other malignant / borderline haematological conditions (myelodysplasia and myeloproliferative disorders), and on imaging. These all reflect important changes in the focus of the speciality in recent years.

Aimed at paediatric oncologists, and trainees in oncology and paediatrics, this leading text will also appeal to paediatric nurses, cancer nurses, and paramedical paediatric staff.

Readership: Aimed at paediatric oncologists, and trainees in oncology and paediatrics, this leading text will also appeal to paediatric nurses, cancer nurses, and paramedical paediatric staff.

New to this edition

• New chapters on clinical trials, evidence based practice, the treatment of cancer in less well-resourced countries, stem cell and immunotherapy, other malignant / borderline haematological conditions (myelodysplasia and myeloproliferative disorders), and on imaging

Reviews

This fourth edition is a necessary modern review of paediatric malignancies and their management. It has been carefully reviewed and updated by leading figures in their disease specific fields... the book can be highly recommended for its homogenous high quality chapters and well balanced approach, and will be required reading for all trainees and consultants involved in the care of paediatric oncology patients... it represents one of the most up to date and useful reviews in paediatric oncology.
- CME Oncology

Table of Contents

1. C. A. Stiller and A. Shah: The epidemiology of cancer in children and adolescents
2. H. Kovar and S. Izraeli: The biology of cancer in children
3. Keiran McHugh and Thierry Huisman: Imaging in paediatric oncology
4. Arnauld Verschuur and Michel Zwaan: Chemotherapy: current knowledge and new perspectives
5. Mark Gaze and Tom Boterberg: Radiotherapy in paediatric oncology
6. Kathy Pritchard-Jones and Maria Grazia Valsecchi: Clinical trials in childhood cancer
7. Rupert Handgretinger and R. Maarten Egeler: Allogeneic stem cell and immunotherapy
8. J.C. Chisholm and M.D. van de Wetering: Supportive care during treatment
9. Martha Grootenhuis, Esther Meijer-van den Bergh, Jantien Vrijmoet-Wiersma and Momcilo Jankovic: Psychosocial care
10. Michelle Koh, Finella Craig and Joanne Wolfe: Palliative care for children with advanced cancer
11. Elizabeth Molyneux and Scott C. Howard: Cancer treatment in low- and middle-income countries
12. Lars Hjorth, Riccardo Haupt and Rod Skinner: Late effects of therapy and survivorship issues
13. Leontien C.M. Kremer and Bob S. Phillips: Evidence based paediatric oncology
14. Rob Pieters and Martin Schrappe: Acute lymphoblastic leukemia
15. Gertjan J.L. Kaspers and Dirk Reinhardt: Acute myeloid leukemia
16. Henrik Hasle and Charlotte Niemeyer: Myelodysplastic syndrome, myeloid leukaemia of Down syndrome, and juvenile myelomonocytic leukaemia
17. Angelo Rosolen and Thomas Gross: Malignant Non-Hodgkin lymphomas in children
18. Robert J Johnston, Dieter Korholz and W. Hamish B. Wallace: Hodgkin's lymphoma: Modern management of children and young adults
19. M. Aricò and S. Weitzman: The histiocytoses
20. Stuart Smith, Franck Bourdeaut, Frank Saran, Francois Doz and David A. Walker: Tumours of the central nervous system
21. Gianni Bisogno and Andrea Ferrari: Soft tissue sarcomas
22. Michael Paulussen, Stefan S. Bielack, H. Kovar, Herbert Jürgens and Mark L. Bernstein: Bone tumours
23. Norbert Graf and Christophe Bergeron: Wilms' and other renal tumours
24. Angelika Eggert and Alberto Garaventa: Neuroblastoma
25. Gabriele Calaminus and James C. Nicholson: Germ cell tumours
26. Giorgio Perilongo and Jozsef Zsiros: Childhood liver tumours
27. Guillermo L. Chantada and Carlos Rodríguez Galindo: Retinoblastoma
28. Beatriz de Camargo, Yves Reguerre and Daniel Orbach: Other rare tumours

Authors

Michael C. G. Stevens, Professor of Paediatric Oncology, University of Bristol and Consultant Paediatric Oncologist Bristol Royal Hospital for Children Professor of Paediatric Bristol, UK,
Hubert N. Caron, Professor of Paediatric Oncology, Emma Kinder Ziekenhuis, Academic Medical Centre, University of Amsterdam, The Netherlands,
Andrea Biondi, Professor of Pediatrics, University of Milano-Bicocca; Director, Department of Pediatrics, Hospital S.Gerardo/Fondazione MBBM, Monza, Italy

Contributors:

Charles Stiller, Childhood Cancer Research Group, University of Oxford, UK
Anjali Shah Childhood Cancer Research Group University of Oxford and London School of Hygiene and Tropical Medicine, UK
Heinrich Kovar, Professor of Molecular Biology Children's Cancer Research Institute St Anna Children's Hospital Wien, Austria
Keiran McHugh, Consultant Paediatric Radiologist, Great Ormond Street Hospital for Children, London, UK
Thierry HuismanThierry A.G.M. Huisman Professor of Radiology and Radiological Science Director Division of Pediatric Radiology Russell H. Morgan Department of Radiology and Radiological Science Johns Hopkins Hospital Baltimore, USA
Arnauld Verschuur, Département de Cancérologie Pédiatrique, Hôpital d'Enfants de La Timone, Marseille, France and, Department of Paediatric Oncology, Emma Children's Hospital AMC University of Amsterdam Amsterdam, The Netherlands
Michel Zwaan, Associate Professor of Pediatric Oncology Dept of Pediatric Oncology Sophia Children's Hospital/Erasmus MC Rotterdam, the Netherlands
Mark Gaze, Department of Oncology, University College London Hospitals NHS Foundation Trust and Great Ormond Street Hospital for Children NHS Trust, London, UK
Tom Boterberg, Department of Radiation Oncology, Ghent University Hospital, Ghent, Belgium
Kathy Pritchard-Jones, Professor of Paediatric Oncology, University College London Institute of Child Health and Consultant Paediatric Oncologist, Great Ormond Street Hospital for Children, London, UK
Maria Grazia Valsecchi, Professor of Medical Statistics, Center of Biostatistics for Clinical Epidemiology, Department of Clinical Medicine and Prevention, University of Milano-Bicocca, Italy
Rupert Handgretinger, Chairman, Department of Hematology/Oncology and General Pediatrics, Children's University Hospital, Tuebingen, Germany
R. Maarten Egeler, Professor of Paediatrics University of Toronto Director, Stem Cell Transplantation The Hospital for Sick Children Toronto, Canada
Julia Chisholm, Paediatric Oncologist, Royal Marsden Hospital, Sutton , UK
Martha A. Grootenhuis Psychosocial Department, Emma Children's Hospital AMC University of Amsterdam Amsterdam, The Netherlands
Marianne D. van de Wetering Department of Paediatric Oncology Emma Children's Hospital AMC University of Amsterdam Amsterdam, The Netherlands
Esther Meijer-van den Bergh, Clinical psychologist, Department of Medical Psychology, University Medical Centre St Radboud, Nijmegen, The Netherlands
Jantien Vrijmoet-Wiersma, Health psychologist, Den Haag, The Netherlands
Momcilo Jankovic, Pediatric Oncologist, Department of Paediatrics, University of Milano-Bicocca, Hospital San Gerardo,Fondazione MBBM, Monza, Italy
Michelle Koh, Palliative Care Consultant, Department of Palliative Care, Great Ormond Street Hospital for Children, London, UK
Finella Craig, Lead Palliative Care Consultant, Department of Palliative Care, Great Ormond Street Hospital for Children, London, UK
Joanne Wolfe, Director, Pediatric Palliative Care, Children's Hospital Boston; Division Chief, Pediatric Palliative Care Service, Department of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute, Boston, USA
Elizabeth Molyneux, Professor of Paediatrics, College of Medicine, Blantyre 3, Malawi
Scott C. Howard, Department of Oncology and International Outreach Program, St. Jude Children's Research Hospital, Memphis, USA
Lars Hjorth, Consultant Paediatric Oncology & Haematology, Department of Paediatrics Lund, Skåne University Hospital, Clinical Sciences Lund University, Lund, Sweden
Riccardo Haupt, Consultant Pediatrician, Epidemiology and Biostatistics Section, Scientific Directorate, G. Gaslini Children's Hospital, Genova, Italy
Rod Skinner, Consultant / Clinical Senior Lecturer in Paediatric & Adolescent Oncology / BMT, Department of Paediatric & Adolescent Haematology Oncology, and Children's BMT Unit, Great North Children's Hospital, Royal Victoria Infirmary, Newcastle upon Tyne, UK
Leontien C.M. Kremer, Department of Paediatric Oncology, Emma Children's Hospital AMC, University of Amsterdam, The Netherlands and Coordinator Editor of the Cochrane Childhood Cancer Group Robert S Phillips Centre for Reviews and Dissemination, University of York, and Paediatric Oncologist Leeds Children's Hospital Leeds General Infirmary, Leeds, UK
Rob Pieters, Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands
Martin Schrappe, Director, and Professor of Pediatrics Department of General Pediatrics , University Hospital Schleswig-Holstein, Kiel, Germany
Gertjan J.L. Kaspers, Pediatric Oncology/Hematology, VU University Medical Center, Amsterdam, The Netherlands
Dirk Reinhardt, Pediatric Oncology/Hematology, Medical School Hannover, Germany
Henrik Hasle, Professor, MD, PhD, Department of Pediatrics, Aarhus University Hospital Skejby, Aarhus, Denmark
Charlotte M. Niemeyer, University Children's Hospital, University of Freiburg, Germany
Angelo Rosolen, Hemato-Oncology Unit Department of Pediatrics, University of Padova, Padova, Italy
Thomas Gross, Gordon Teter Chair for Pediatric Cancer Research, andProfessor, Department of Pediatrics, OSU School of Medicine, Nationwide Children's Hospital, Columbus, USA
Robert J. Johnston,Consultant in Paediatric Oncology Royal Belfast Hospital for Sick Children Belfast, UK
Dieter Korholz, Professor of Pediatrics, Director Clinic for children and adolescents, Martin Luther University halle/Wittenberg, Halle, Germany
W. Hamish B. Wallace, Professor of Paediatric Oncology, Royal Hospital for Sick Children, Edinburgh, UK
Sheila Weitzman, Associate Director (Clinical), Division of Hematology/Oncology, The Hospital for Sick Children, Toronto; and Professor of Pediatrics , University Of Toronto, Canada
M. Aricò, M.Arico Director, Department Pediatric Hematology Oncology , Azienda Ospedaliero-Universitaria Meyer, Florence, Italy
Francois Doz,Department of Paediatric Oncology, Institut Curie, and Professor of Paediatrics, University Paris Descartes, Sorbonne Paris Cité, France
Franck Bourdeaut, Department of paeditric oncology & INSERM U830, Institut Curie , Paris, France
David A. Walker, Children's Brain Tumour Research Centre, School of Clinical Sciences, University of Nottingham, UK
Stuart Smith, FRCS (Neurosurg),Children's Brain Tumour Research Centre, School of Clinical Sciences, University of Nottingham, UK
Frank Saran, Consultant Clincial Oncologist, Department of Paediatric Oncology, The Royal Marsden NHS Foundation Trust, Sutton, UK
Gianni Bisogno, Hematology Oncology Division, Department of Pediatrics, University Hospital of Padova, Padova, Italy
Andrea Ferrari, Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy
Michael Paulussen, MD Medical Director, Vestische Kinder- und Jugendklinik Datteln, Germany. Chair of Paediatrics, Faculty of Health, Witten/Herdecke University Datteln, Germany
Stefan S. Bielack, Klinikum Stuttgart, Zentrum für Kinder- und Jugendmedizin - Olgahospital Pädiatrie 5 (Onkologie, Hämatologie, Immunologie; Allgemeine Pädiatrie, Gastroenterologie, Rheumatologie) Stuttgart, Germany
Herbert Jürgens, Universitätsklinikum Münster, Klinik und Poliklinik für Kinderheilkunde - Päd. Hämatologie/Onkologie, Münster, Germany
Mark L. Bernstein, Division of Pediatric Hematology-Oncology, IWK Health Centre, Dalhousie University, Halifax, Canada
Norbert Graf, Director of the Department for Pediatric Hematology and Oncology, Saarland University, Medical Faculty, Homburg, Germany
Christophe Bergeron, Paediatric oncologist and Head of <"Institut d'Hématologie et d'Oncologie Pédiatrique", Lyon, France
Angelika Eggert, Professor of Pediatrics, University Children's Hospital Essen, Germany
Alberto Garaventa, Oncology Unit, Department of Pediatric Haematology-Oncology, Giannina Gaslini Childrens Hospital, Genova, Italy
Gabriele Calaminus Consultant Pediatric Hematologist/Oncologist University Childrens Hospital Münster Department of Pediatric Hematology and Oncology Münster, Germany
James Nicholson, Consultant Paediatric Oncologist, Cambridge University Hospitals NHS Trust, UK
Giorgio Perilongo, Pediatric Oncology Department Centre Hospitalier Universitaire Angers, France
Jozsef Zsiros, Department of Paediatric Oncology Emma Children's Hospital AMC University of Amsterdam Amsterdam, The Netherlands
Guillermo L. Chantada, Principal Physician, Hemato-oncology service, Hospital JP Garrahan, Buenos Aires, Argentina
Carlos Rodriguez-Galindo, MD, Department of Pediatric Oncology, Dana-Farber/Children's Hospital Cancer Center, Associate Professor of Pediatrics, Harvard Medical School, Boston, USA
Beatriz de Camargo, Pediatric Hematology-Oncology Program Instituto Nacional do Cancer, Rio de Janeiro, Brazil
Yves Reguerre, Oncologic Pediatric department, Centre hospitalo-universitaire, Angers, France
Daniel Orbach, Pediatric department, Institut Curie, Paris, France