- Carefully tailored in terms of breadth and depth to the needs of medicine and biomedicine students: covers all the essential concepts without extraneous details;
- Short, focused chapters and clear, uncluttered design make the book easy to navigate and extract information from;
- Custom-drawn figures and photomicrographs complement the text, helping the reader to grasp key concepts;
- An Online Resource Centre features additional teaching and learning materials.
New to this edition
- Greater explanation of virology at the molecular level, supported by new figures.
- Increased coverage of viral replication.
- Many chapters introduced by new 'Fundamental Concepts' panels, including viral lifecycle boxes, and timelines to show significant landmarks following the discovery of a virus, to give an at-a-glance overview of the topic.
- Case studies throughout illustrate the clinical relevance of the subject.
Viruses are the ultimate parasites: they infect cells and hijack their molecular machinery in order to survive, often destroying the host cell in the process. In so doing, they present a major challenge to human health and well-being, with the continual emergence of new viral strains placing huge demands on healthcare systems internationally.
Human Virology is the perfect introduction to the subject for anyone who needs to understand how viruses impact on human health, and how they can be managed in a clinical context. It does not seek to turn its readers into virologists, but to provide them with enough knowledge of the nature of viruses and viral infections to serve as an essential foundation for anyone encountering viruses in a clinical or biomedical context.
Capturing this complex and rapidly-evolving subject with remarkable clarity, Human Virology describes the general principles of viral biology - the properties of viruses, their replication and genetics - along with disease and resistance, before introducing the infections caused by key groups of viruses. It concludes with an overview of the management of viral disease, including diagnosis and immunization.
Reflecting our latest understanding of the molecular basis of viral diseases, Human Virology is the ideal resource for all students of medicine, dentistry, and the biological and biomedical sciences, who need a clear and focused introduction to the subject.
The Online Resource Centre to accompany Human Virology features: For lecturers:
Figures from the book in electronic format
Hyperlinked bibliography that takes you directly to the articles mentioned in the textbook
Oxford NewsNow - The latest news relevant to human virology
Useful weblinks to help you research and revise
Readership: Medical and dental students studying virology, microbiology students, and students studying immunology and biomedical sciences.
Leslie Collier, Emeritus Professor of Virology, University of London., John Oxford, Professor of Virology, St Bartholomew's and the Royal London Hospital School of Medicine and Dentistry., and Paul Kellam, Virus Genomics Team Leader, Sanger Institute, Cambridge.
Review(s) from previous edition
"Covers all the bases well, with no major topic omitted. The authors' style is very "student friendly" and, sometimes, almost conversational in tone. This makes the book very easy to read. Layout is also user friendly with good use of tables/graphs/pictures. Reminders at each chapter end and appendices are also useful. - Professor Kevin Kerr, Harrogate District Hospital.
"It is very comprehensive and covers most viruses that we encounter in clinical practice. I like the way how the chapters are divided into different types of viruses, its properties and clinical aspects of diseases. Chapter 7 is particularly useful as it mentions virus interaction in the community. Epidemiology is still an aspect that many people take for granted, but I think its an important element in virology. " - Dr Norzeihan Jan Bappu, Foundation 1 Doctor.
TABLE OF CONTENTS
Part 1 General Principlpes
1: Virology: How it all began
2: General properties of viruses
3: Viral replication and genetics
4: How viruses cause disease
5: Resistance of the human body to virus infections
6: Viruses and cancer in humans
7: Viruses and the community
Part 2 Special Infections
8: Upper respiratory tract and eye infections due to adenoviruses, coronaviruses (including SARS CoV), and rhinoviruses
9: Infections caused by paramyxoviruses: measles, RSV, mumps, parainfluenza, meta-pneumoviras and the henipaviruses
10: Orthomyxoviruses and influenza
11: Gastroenteritis viruses
12: Rubella: postnatal infections
15: Papilloma - and polyomavirus
16: Poliomyelitis and other picornavirus infections
17: The herpesviruses: general properties
18: The alphaherpesviruses: herpes simplex and varicella-zoster
19: The betaherpesviruses: cytomegalovirus and human herpesviruses 6 and 7
20: The gammaherpesviruses: Epstein-Barr virus and Kaposi's sarcoma-assocociated herpesvirus
21: Introduction to the hepatitis viruses
22: The blood-borne hepatitis viruses B and D
23: The blood-borne hepatitis C
24: The enteric hepatitis viruses A and E
25: Retroviruses and HIV
26: Lyssavirus and rabies
27: Arthropod-borne viruses
28: Exotic and dangerous infections: filoviruses and arenaviruses
29: Prions and the spongiform encephalopathies
Part 3 Special Syndromes
30: Viral diseases of the central nervous system
31: Intrauterine and perinatal infections
32: Viral infections in patients with defective immunity
33: Respiratory Infections
34: Sexually transmitted viral infections
35: Resurgent and emergent viral infections
Part 4 Practical Aspects
36: The laboratory diagnosis of viral infections
37: Control of viral diseases by immunization
38: Antiviral chemotherapy
A Safety precautions: codes of practice, disenfection, and sterilization
B Viral infections notifiable in the UK
C Suggestions for futher reading