- This fully updated and restructured new edition, which includes five new chapters, takes account of new developments in the field and presents them in a logical, coherent way.
- The author's widely-praised writing style leads the reader through a conceptually challenging subject in a clear, lucid way, building confidence in, and enthusiasm for, the subject at the outset.
- New ethics boxes dispersed throughout the text alert the reader to the ethical issues surrounding the subject.
- Special topic boxes and case studies augment the main text, enable flexibility of use, and offer an extra level of detail for those studying the topic at a more advanced level.
- Extensive learning tools throughout - most notably end of chapter exercises, problems and weblems - encourage and support self-directed learning, helping the student to master the subject through hands-on learning.
- An Online Resource Centre features an extensive range of resources for both lecturers and students, enhancing the value of the book as a teaching and learning tool.
New to this edition
- New, larger format provides greater clarity to the text and accompanying figures.
- Five new chapters, including one dedicated to metabolomics.
- Ethics boxes alert the reader to the complexity of the ethical issues surrounding the study of genomics.
- Highlighted key terms are collated in a glossary at the end of the book.
Our genome is the blueprint to our existence: it encodes all the information we need to develop from a single cell into a hugely complicated functional organism. But it is more than a static information store: our genome is a dynamic, tightly-regulated collection of genes, which switch on and off in many combinations to give the variety of cells from which our bodies are formed. But how do we identify the genes that make up our genome? How do we determine their function? And how do different genes form the regulatory networks that direct the processes of life?
Introduction to Genomics is a fascinating insight into what can be revealed from the study of genomes: how organisms differ or match; how different organisms evolved; how the genome is constructed and how it operates; and what our understanding of genomics means in terms of our future health and wellbeing.
Covering the latest techniques that enable us to study the genome in ever-increasing detail, the book explores what the genome tells us about life at the level of the molecule, the cell, and the organism. Learning features throughout make this book the ideal teaching and learning tool: extensive end of chapter exercises and problems help the student to fully grasp the concepts being presented, while end of chapter weblems (web-based problems) and lab assignments give the student the opportunity to engage with the subject in a hands-on manner.
The field of genomics is enabling us to analyze life in more detail than ever before; Introduction to Genomics is the perfect guide to this enthralling subject.
Online Resource Centre
The Online Resource Centre to accompany Introduction to Genomics features
Figures from the book in electronic format
Answers to end-of-chapter exercises
Guided tour of web sites in genomics
Hints to end-of-chapter problems
Table of contents
1: Introduction to Genomics
2: Genomes are the Hub of Biology
3: Mapping, Sequencing, Annotation, and Databases
4: Comparitive Genomics
5: Evolution and Genomic Change
6: Genomes of Prokaryotes
7: Genomes of Eukaryotes
8: Genomics and Human Biology
9: Microarrays and Transcriptomics
11: Systems Biology