- A compact guide to the latest evidence-based practice in hyperlipidaemia
- Advocates a practical approach to management, including therapies and other interventions
- Describes how the condition might be prevented, as well as looking to future treatment
In the last decade, advances in the understanding of lipoprotein and lipid metabolism have developed enormously. This has resulted in a detailed knowledge of the mechanisms underlying the primary and secondary dyslipidaemias. Furthermore, the role of lipoproteins in atherogenesis is increasingly understood at the cellular and molecular level.
In this book, the scale of the problem of cardiovascular disease (CVD) is described together with the possibilities for prevention. The pathophysiology of lipid and lipoproteins provide a background to the understanding of the primary and secondary dyslipidaemias and the mechanism of action of the different drug classes.
A practical approach to therapy is provided including diet, lifestyle, and
therapeutic approaches. Common clinical problems are addressed and the book
looks to the future, principally in relation to new therapeutic targets. This
book provides the basis for the translation of clinical trial science into everyday
clinical practice for the benefit of the individual patient.
Readership: The book is aimed at trainee clinicians, general practitioners, nurse specialists, and related health care professionals.
Table of Contents
1: Professor Guy De Backer: Epidemiology of cardiovascular disease: the scale
of the problem
2: Joanna Gouni-Berthold and Wilhelm Krone: Lipids, lipoproteins and atherogenesis
3: Catherine McGorrian, Tora Leong, Ralph D'Agostino, Marie-Therese Coney and Ian M. Graham: Risk estimation systems in clinical use: SCORE, HeartScore, Framingham, PROCAM, ASSIGN and QRISK
4: Anton F. H. Stalenhoef: Primary dyslipidaemias
5: Rafael Carmena and José T Real: Secondary dyslipidemias
6: Jonathan Morrell and Jacqueline Morrell: Diet and lifestyle
7: D. John Betteridge: Pharmacological therapy: Statins
8: D. John Betteridge: Pharmacological therapy: Non-Statin Drugs
9: Anthony S. Wierzbicki: Combination therapy for the management of hyperlipidaemia
10: D. John Betteridge: Recent lipid-lowering trials in perspective: Implications for therapy
11: Manish Kalla and Julian Halcox: Vascular imaging
12: John Reckless: Common problems in lipid management