1: What is addiction?
2: Burden of addiction
3: Key elements of addiction
4: Neurobiological processes in addiction
5: Drug pharmacokinetics and abuse liability
6: Pharmacodynamics of addictive substances
7: The dopamine system and addiction
8: The GABA system and addiction
9: The glutamate system and addiction
10: The opioid system and addiction
11: Nicotine addiction
12: Appetite hormones and addiction
13: Conclusion and overview
- Contains full-colour images to illustrate discussions
- Easily portable, in an accessible format for quick-reference
- Helpful 'key points' sections at the start of each chapter
New to this Edition:
- Two new chapters on 'Nicotine addiction' and 'Appetite hormones and addiction'
Substance addiction is a chronic, relapsing disorder characterized by a compulsion to take a substance despite potential consequences.
Addiction, second edition offers a clear and succinct overview of the brain science underpinning substance addiction. Focusing on the nature of addiction as a brain disorder, this resource discusses a range of different behavioural traits such as impulsivity and reward dependence, and looks at the critical role of kinetic and pharmacological factors.
All chapters have been fully updated to provide readers with a quick-reference guide to the latest research on pharmacological and non-pharmacological treatments for addition, and feature helpful key points and further reading sources. In addition, two new chapters on nicotine addiction and appetite hormones have been added to ensure the reader is kept abreast of the most recent discussions in the field of research.
David J. Nutt, The Edmond J Safra Chair in Neuropsychopharmacology, Centre for Neuropsychopharmacology, Division of Brain Sciences, Department of Medicine, Imperial College London, and Liam J. Nestor, Research Fellow, Centre for Neuropsychopharmacology, Division of Brain Sciences, Department of Medicine, Imperial College London