Full Author: Edited by: Gianni Marone Universita degli Studi di Napoli Federico II, Napoli, Italy K.F. Austen Boston, Massachusetts S.T. Holgate Southampton General Hospital, Southampton, UK A.B. Kay National Heart and Lung Institute, London, UK L.M. Lichtenstein Johns Hopkins University School of Medicine, Baltimore, Maryland
Description: This book updates the previous coverge of the mechanisms amd mediators of asthma and its treatment. It presents articles by the foremost names in the field.
Features: Updates the previous coverage of the mechanism and mediators of asthma and its treatment. Presents articles by the foremost names in the field. Includes over 92 figures and 12 tables.
The Genetic and Epidemiology of Atopy and Asthma: J-L. Zhao, K.F. Austen, and B.K. Lam, Prospective on the Functional Characteristics of Human LTC Synthase. W.O.C.M. Cookson, Genetics and Asthma. I.M. Adcock and P.J. Barnes, Transcription factors in Asthma. U. Wahn, Environmental Factors in the Development of Atopy and Asthma in Children. Signal Transduction in Immune and Inflammatory Cells: M-H. Jouvin and J-P. Kinet, Expression and Function of the High-Affinity Receptor for IgE in Asthma. J.T. Schroeder, D.W. MacGlashan, Jr., and L. M. Lichtenstein, The Role of Basophil-Cytokine Networks in Asthma. A. Mantovani, A. Sica, S. Saccani, S Orlando. N Polentartutti, P. Allavena, and S. Soxxani, Regulation of Inflamatory Cytokine Receptor Expression by Pro- and Anti-Inflamatory Molecules. H.R. Katz, The gp49 Family: A New Pathwas for the Inhibition of Mast Cell Activation. J.M. Langdon and S. MacDonald, Biological Properties of the IgE-Depentent Histamine Releasing Factor. Chemical mediators in Allergic Disorders: A.F. Walls, J.K. Shute, J. Warner, J.A. cairns, P.H. Hawarth, and S.T. Holgate, Mast cell and Eosinophil Proteases in the Chronic Allergic Inflammatory Response. M. Triggiani and G. Marone, Remodelling of Arachidonic Acid Pools in Inflammatory Cells Migrating to the Lungs. D. Proud, C.J. Reynolds, J.M. Bathon, and A. Faussner, Kinin Actions in the Human Airways: Modulation by Allergic Inflamation. M. Baggiolini, M. Uguccioni, and P. Loetscher, Chemokines and Chemokine Receptors in Allergic Inflammation. Molecular Regulation of Cytokine Genes: S.N. Georas, T.F Burke, R. Chen, J. Cumberland, and V. Caolaro, The Molecutal Basis of IL-4 Dysregulation in the Atopic Condition. D.J Cousins, D.Z. Staynoff, and T.H. Lee, Regulations of IL-4, IL-5 and GM-CSF in T-Lymphocytes. Immune and Inflammatory Cells in Allergic Disorders: A.B. Kay, T-Lymphocytes in Chronic Asthma. L.B. Schwartz, Mast Cells and Asthma. Cardiac Mast Cells and Their Role in Severe Allergic Reactions. G.J. Gleich, J. Bankers-Fulbright, S. Okada, H. Kita and L.W. Hunt, Novel Glucocoticomimetic Agents Active on Eosinophiles: Potential Uses in the Therapy of Asthma. Biophysical and Immunological Alterations in Atopic Patients: S. Seidenari, Biophysical Evaluation of Skin Reactivity in Atopic Patients. E.W. Gelfand, G. Lack, A. Oshiba, and E. Hamelmann, Role of Allergen-Specific B Cells and IgE in the Developmetn of Allergen-Driven Ariways Hyperresponsiveness. Cytokines and Inflammation in the Airways: J.E. Germ, R.F. Lemanske, and W.W. Busse, Role of Rhinoviruses in Virus-Induced Asthma. G. Ciprandi, G. Passalacqua, B. Azzoarone, M. Bagnasco, and G.W. Canonica, Molecular Events in Allergic Inflammation: Expression of Adhesion Molecules and Their Modulation. J.C. Hogg, V. Macek, A. Dakhama, S. Hayashi, and R.G. Hegele, The Prevalence of Common Respiratory Viral Nucleic Acid in Asthmatic and Non-Asthmatic Human Lung. Prospectives in Therapy of Allergic Disorders: R.P. Scheimer and Q. Hamid, Regulation of Allergic Airways Inflammation by Cytokines and Glucocorticoids. J.M. Drazen, Interfering with the 5-Lipoxygenase Pathway as a Novel Way to Treat Asthma, J.A. Grant, New Aspects of Antihistamines in the Treatment of Asthma. W.J. Metzar and J.A. Nyce, DNA Antisense Therapy for Asthma. Prospectives in Immunotherapy of Allergic Disorders: T.A.E Platts-Mils, Prospectives in Allergen Specific Treatment. P.S. Creticos, Peptide Downregulation of the Immune Response. E. Raz, Immune Deviation of the Allergic Response by DNA Immunization.