Environmental toxicology is generally held to be the study of the potential of constituents of outdoor environments to impact either human health or the biological structure of the ecosystems involved. This volume is a first attempt to integrate toxicological studies of all of the many human environments, both indoor and outdoor, and their complex interrelationships. Included are considerations of natural environments, the agroecosystem, occupational, urban and domestic environments as well as the environment associated with Superfund sites and military deployments.
The primary emphasis is on public health, including the potential health effects of toxicants found in different environments, the bioprocessing of such toxicants in humans and surrogate animals and the principles of risk analysis.
- Approaches the toxicology of human environments in a new and unique way, stressing the complex interrelationships of all human environments and the implication for human and environmental health
- Each chapter is written by an acknowledged expert and is addressed to those interested in the broader implications of the environmental modifications that are always associated with the activities of humans living and working in them.
Table of Contents
Human Environments: Definition, Scope and the Role of Toxicology
Estimating Human Exposure: Improving Accuracy with Chemical Markers
Roger C. Cochran and Jeffrey H. Driver
Metabolism of Xenobiotics Human Environments
Toxic Endpoints in the Study of Human Exposure to Environmental Chemicals
Andrew D. Wallace
Pesticide Regulations: Exposure-Dose Modeling from FIFRA to FQPA
James B. Knaak, Cecilla Tan and Curt C. Dary
Occupational Chemicals: Metabolism, Toxicity and Mode of Action
Sheila Flack and Leena A. Nylander-French
Chemicals of Military Deployments: Revisiting Gulf War Syndrome in Light of
Pharmaceuticals in the Environment: Lessons Learned for Reducing Uncertainties
in Environmental Risk Assessment
Bryan W. Brooks, Jason P. Berninger, Lauren A. Kristofco, Alejandro J. Ramirez, Jacob K. Stanley and Theodore W. Valenti
Quantitative Risk Assessment Methods for Cancer and Non-Cancer Effects
Ronald E. Baynes
Human Health Risk Assessment for Contaminated Properties
Atul M. Salhotra
The Future of Human Health Risk Assessment of Environmental Chemicals.
Ecological Risk Assessment
Damian Shea and Waverly Thorsen
Metabolic Interactions of Environmental Toxicants in Humans
Toxins and Venoms
Summary and Conclusions
Ernest Hodgson, PhD, Distinguished Professor Emeritus, Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC, USA