


Progress in Molecular Biology and Translational Science, Vol. 115: Oligomerization and Allosteric Modulation in G-Protein Coupled Receptors
Kenakin, T.
ISBN-13: 9780123945877
ACADEMIC PRESS
Abril / 2013
1ª Edición
Inglés
Tapa dura
476 pags
724 gr
16 x 24 x 3 cm
Recíbelo en un plazo De 7 a 10 días
Description
In this thematic volume of Progress in Molecular Biology and Translational Science, researchers reflect on recent developments and research surrounding G protein-coupled receptors. The chapters cover a large breadth of research, including GPCR role in stem cell function and pharmacology.
Authors explore in-depth research techniques and applications of GPCR usage, covering theory, laboratory approaches, and unique qualities that make GPCRs a crucial tool in microbiological and cancer research.
Table of Contents
- Approaches for Probing Allosteric Interactions at 7 Transmembrane Spanning
Receptors
Michael T. Klein, Paige N. Vinson and Colleen M. Niswender - Pharmacology of Metabotropic Glutamate Receptor Allosteric Modulators:
Structural Basis and Therapeutic Potential for CNS Disorders
Karen J. Gregory, Meredith J. Noetzel and Colleen M. Niswender - Mining the Potential of Label-Free Biosensors for Seven-Transmembrane Receptor
Drug Discovery
Magalie Rochville, Julio Martin, Jeffrey Clifford Jerman & Evi Kostenis - G Protein-Coupled Receptors in Cancer : Biochemical Interactions and Drug
Design
Yves Audigier, François-Xavier Picault, Carline Chaves-Almagro and Bernard Masri - GPCRs in Stem Cell Function
Van A. Doze and Dianne M. Perez - Application of Receptor Theory to Allosteric Modulation of Receptors
David A. Hall - What Ligand-Gated Ion Channels Can Tell Us about the Allosteric Regulation
of G protein-Coupled Receptors
Frederick J. Ehlert - Modelling Cooperativity Effects in Dimeric G Protein-Coupled Receptors
Jesús Giraldo - Chemokine Receptor Oligomerization and Allostery
Bryan Stephens and Tracy M. Handel - Fine-Tuning of GPCR Signals by Intracellular G Protein Modulators
Peishen Zhao, Wendy Cladman, Hubert HM Van Tol and Peter Chidiac
Author Info
Terry Kenakin, PhD, Professor of Pharmacology, The University of North Carolina at Chapel Hill
Fax91 448 21 88
DirC / Raimundo Lulio, 1, 28010 Madrid, España.
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