Natural Product Biosynthesis by Microorganisms and Plants Part B (Methods in Enzymology, Vol. 516)

Description

This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The second of 3 volumes covering Natural product biosynthesis by microorganisms and plants.

Table of Contents

1. In vivo production of thiopeptide variants
   Feifei Zhang and Wendy L. Kelly
2. Microviridin biosynthesis
   Thomas K. Hemscheidt
3. Cyclotide isolation and characterization
   David J. Craik, Sonia Troeira Henriques, Joshua S. Mylne and Conan K. Wang
4. Ribosomally-encoded cyclic peptide toxins from mushrooms
   Jonathan Walton, Hong Luo, and Heather Hallen-Adams
5. The Pictet-Spengler mechanism involved in the biosynthesis of tetrahydroisoquinoline antitumor antibiotics: novel function for a non-ribosomal peptide synthetase
   Kento Koketsu, Atsushi Minami, Kenji Watanabe, Hiroki Oguri and Hideaki Oikawa
6. Discovery and biosynthesis of phosphonate and phosphinate natural products
   Spencer C. Peck, Jiangtao Gao, and Wilfred A. van der Donk
7. RlmN and AtsB as models for the overproduction and characterization of radical SAM proteins
   Nicholas D. Lanz, Tyler, L. Grove, Camelia Gogonea, Carsten Krebs, and Squire J. Booker
8. Fe(II)-dependent, uridine-5’-monophosphate a-ketoglutarate dioxygenases in the synthesis of 5’-modified nucleosides
   Zhaoyong Yang, Jason Unrine, Koichi Nonaka, and Steven G. Van Lanen
9. Heme-dependent Tailoring Enzymes in Natural Product Biosynthesis: Spectroscopic Characterisation of the L-tryptophan-nitrating Cytochrome P450 TxtE
   S. M. Barry and Greg Challis
10. Oxidative Tailoring Reactions Catalysed by Non-heme Iron-dependent Enzymes: Streptorubin B Biosynthesis as an Example
    Paulina K. Sydor and Greg Challis
11. The rare fluorinated natural products and biotechnological prospects for fluorine enzymology
    K. K. Jason Chan and David O’Hagan
12. Enzymatic chlorination and bromination
    Karl-Heinz van Pée
13. Prenyltransferases of the dimethylallyltryptophan synthase superfamily
    Xia Yu and Shu-Ming Li
14. Serine carboxypeptidase-like acyltransferases from plants
    Sam T. Mugford and Carsten Milkowski
15. 4-Methylideneimidazole-5-one-containing aminomutases in enediyne biosynthesis
    Jeremy R. Lohman and Ben Shen
16. Tailoring enzymes acting on carrier protein-tethered substrates in natural product biosynthesis
    Shuangjun Lin, Tingting Huang, and Ben Shen
17. High-throughput colorimetric assays for nucleotide sugar formation and glycosyl transfer
    Richard W. Gantt and Jon S. Thorson