Full Author: Vincent T. Andriole Yale University School of Medicine, New Haven, Connecticut Description: The Quinolones, Second Edition provides the most current review of quinolone antibacterial agents available and a look into new quinolone development. The book provides comprehensive and updated coverage of the history, chemistry, pharmacology, efficacy and safety aspects of quinolones. New chapters describe the use of quinolones in treating specific infections, and bacterial meningitis. This text is a valuable reference for primary care physicians and infectious disease specialists as well as researchers and industry personnel involved in the development of new antimicroagents.
Features: * Comprehensive coverage of all aspects of quinolone antibacterials including chemistry, biology, pharmacokinetics, safety, and efficacy * Individual chapters covering the use of quinolones in various medical subspecialities, including surgical infections and obstetrics and gynecology, pediatrics, sexually transmitted diseases, and immunocompromised patients
Contents: P. Ball, The Quinolones: History and Overview. T.D. Gootz and K.E. Brighty, Chemistry and Mechanism of Action of the Quinolone Antibacterials. I. Phillips, A. King, and K. Shannon, In Vitro Properties of the Quinolones. T. Kohler and J.C. Pechere, Bacterial Resistance to Quinolones: Mechanism and Clinical Implications. T. Bergan, Pharmacokinetics and Pharmacodynamics of Quinolones. L.E. Nicolle, Use of the Quinolones in Urinary Tract Infection and Prostatitis. R.P DiCarlo and D.H. Martin, Use of the Quinolones in Sexually Transmitted Diseases. M. Niederman, Treatment of Respiratory Tract Infections with Quinolones. S. Faro and J. Weigelt, Use of the Quinolones in Surgery and Obstetrics and Gynecology. D.H. Hamer and S.L. Gorbach, Use of the Quinolones for the Treatment and Prophylaxis of Bacterial Gastrointestinal Infections. R. Hasbun and V.J. Quagliarello, Use of the Quinolones in Treatment of Bacterial Meningitis. K.V.I. Rolston, Use of the Quinolones in Immunocompromised Patients. A.W. Karchmer, Use of the Quinolones in Skin and Skin Structure (Osteomyelitis) and Other Infections. U.B. Schaad, Use of the Quinolones in Pediatrics. R. Stahlmann and H. Lode, Safety Overview: Toxicity, Adverse Effects and Drug Interactions. V.T. Andriole, The Quinolones: Prospects. Subject Index.