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Hopkins, Philip M. and Ellis, F.R. (eds.)
This authoritative and comprehensive new publication looks in depth at a range of medical syndromes characterized by serious and unpredicted internal overheating of the body. As a result of heat stress, exceptional physical exertion, or in response to certain drugs, these episodes may arise suddenly and unexpectedly, with life-threatening consequences. This text's contributions focus on the full range of these syndromes, their metabolic and physiological bases, the important predisposing factors that determine those at risk, and the medical management of these conditions. The volume incorporates a wealth of information from the Leeds Malignant Hyperthermia Investigation Unit--the world's leading center of research and investigation in this area.
Contributors: SECTION I: EXERTIONAL HEATSTROKE 1. History and Epidemiology: Definitions and Groups at Risk, J. G. Dickinson/2. Predisposing Factors, Clinical Features, Treatment and Prevention, J. G. Dickinson/3. Pathophysiology of Heatstroke, J. P. Knochel/4. Investigation of Heat Stroke Victims 1: The Human Physiology Laboratory, C. G. Batty & W. A. Freeland/5. Investigation of Heat Stroke Victims 2: Nuclear Magnetic Resonance Spectroscopy, J.-F. Payen & P. Stieglitz/6. Investigation of Exertional Heat Stroke 3: In Vitro Skeletal Muscle Contracture Testing, P. M. Hopkins, P. J. Halsall & F. R. Ellis/7. Future Research in Exertional Heat Stroke, P. M. Hopkins/ SECTION 2: MALIGNANT HYPERTHERMIA 8. The Clinical Presentation of Malignant Hyperthermia, P. J. Halsall/9. Malignant Hyperthermia: Clinical Management, G. A. Gronert & J. F. Antognini/10. Pathophysiology of Malignant Hyperthermia, J. E. Fletcher & H. Rosenberg/11. Screening for Malignant Hyperthermia Susceptibility, P. J. Halsall/12. Skeletal Muscle Morphology, P. Harnden/13. The Genetics of Malignant Hyperthermia, Sarah P. West/14. Porcine Stress Syndrome, J. Dinsmore & G. M. Hall/ SECTION 3. OTHER HYPERMETABOLIC SYNDROMES 15. Neuroleptic Malignant Syndrome, P. J. Adnet, H. Reyford & R. M. Krivosic-Horger/ 16. Hyperthermic and Hypermetabolic Disorders, J. A. Henry/ 17. Hypermetabolism in Endocrine Disorders, P. Belchetz